SynthesisSleep medicine2023
Post-stroke sleep disturbance and recurrent cardiovascular and cerebrovascular events: A systematic review and meta-analysis.
Synthesis in Sleep medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Efficacy and safety of Chinese herbal acupoint application for post-stroke sleep disorders: a systematic review and meta-analysis.Frontiers in neurology · 2026Pooled it
- Sleep Disturbances, Metabolic Markers, and Outcomes After Stroke: A Retrospective Cohort Study in a Tertiary Hospital.Journal of clinical medicine · 2026Article
- Article
- Sleep and Stroke-An Overlooked Bidirectional Influence: Why Should Sleep and Vascular Neurologists Work Closer?Journal of clinical medicine · 2025Article
- Article
- Joint effects of physical activity and sleep quality on all-cause and cardiovascular disease mortality in stroke survivors: a population-based cohort study from the UK-Biobank.BMC public health · 2025Article
- Evaluation of the Prevalence of Sleep Disorders and Their Association with Stroke: A Hospital-Based Retrospective Study.Journal of clinical medicine · 2025Article
- Association of sleep duration and sleep disorders with post-stroke depression and all-cause and cardiovascular disease mortality in US stroke survivors: results from NHANES 2005-2018.European journal of medical research · 2025Article
- Barriers to and facilitators of implementing obstructive sleep apnea screening in stroke patients: a scoping review protocol.Frontiers in neurology · 2025Article
- Continuous positive airway pressure in acute ischemic stroke patients with obstructive sleep apnea: analysis of the National Inpatient Sample database.Frontiers in neurology · 2025Article
- Analysis of the current status and associated factors of depressive symptoms in Chinese middle-aged and elderly stroke patients-based on CHARLS data.Frontiers in psychiatry · 2025Article
- Early screening of sleep disordered breathing in hospitalized stroke patients high-resolution pulse oximetry as prognostic and early intervention tools in patients with acute stroke and sleep apnea (HOPES TRIAL).Sleep & breathing = Schlaf & Atmung · 2024Article
- Clinic and ambulatory blood pressures, blood pressure phenotypes and mortality in patients with a previous stroke.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Observational
- Sleep disorders as both risk factors for, and a consequence of, stroke: A narrative review.International journal of stroke : official journal of the International Stroke Society · 2024Review
- Up-to-date advance in the relationship between OSA and stroke: a narrative review.Sleep & breathing = Schlaf & Atmung · 2024Review
- Exploring common biomarkers of ischemic stroke and obstructive sleep apnea through bioinformatics analysis.PloS one · 2024Article
- Recurrent/Subsequent Stroke and Associated Outcomes in Geriatric Patients with OSA and Prior Stroke Events: A Retrospective Study Using the 2019 National Inpatient Sample.Journal of personalized medicine · 2023Article
- Disparities in brain health comorbidity management in intracerebral hemorrhage.Frontiers in neurology · 2023Article
- Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Despite improvements in survival rates, risk of recurrent events following stroke remains high. Identifying intervention targets to reduce secondary cardiovascular risk in stroke survivors is a priority. The relationship between sleep and stroke is complex: sleep disturbances are likely both a contributor to, and consequence of, stroke. The current aim was to examine the association between sleep disturbance and recurrent major acute coronary events or all-cause mortality in the post-stroke population. Thirty-two studies were identified, including 22 observational studies and 10 randomized clinical trials (RCTs). Identified studies included the following as predictors of post-stroke recurrent events: obstructive sleep apnea (OSA, n = 15 studies), treatment of OSA with positive airway pressure (PAP, n = 13 studies), sleep quality and/or insomnia (n = 3 studies), sleep duration (n = 1 study), polysomnographic sleep/sleep architecture metrics (n = 1 study), and restless legs syndrome (n = 1 study). A positive relationship of OSA and/or OSA severity with recurrent events/mortality was seen. Findings on PAP treatment for OSA were mixed. Positive findings indicating a benefit of PAP for post-stroke risk came largely from observational studies (pooled RR [95% CI] for association between PAP and recurrent cardiovascular event: 0.37 [0.17-0.79], I
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.