Evidence map›Paper›PMID 36888709›Full record

ArticleScience advances2023

Dynamic bioinspired coculture model for probing ER

Lina Pradhan, DeVonte Moore, Elisa M Ovadia, Samantha L Swedzinski, Travis Cossette, Robert A Sikes, Kenneth van Golen, April M Kloxin

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Mechanisms of breast cancer dormancy in bone metastasis.Clinical & experimental metastasis · 2026
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  11. Multi-stage mechanisms of tumor metastasis and therapeutic strategies.Signal transduction and targeted therapy · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lina PradhanDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA.ORCID 0000-0001-9984-5318
DeVonte MooreDepartment of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716, USA.ORCID 0000-0002-2692-9593
Elisa M OvadiaDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA.
Samantha L SwedzinskiDepartment of Materials Science and Engineering, University of Delaware, Newark, DE 19716, USA.ORCID 0000-0001-5071-7681
Travis CossetteOffice of Laboratory Animal Medicine, University of Delaware, Newark, DE 19716, USA.ORCID 0000-0003-0398-5047
Robert A SikesDepartment of Biological Sciences, University of Delaware, Newark, DE 19716, USA.ORCID 0000-0002-9609-4173
Kenneth van GolenDepartment of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
April M KloxinDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA.ORCID 0000-0002-4594-2953
University of Delaware · US

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI Jeffrey L Caplan · 2012 to 2026
$67.2M
This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2014 to 2024
$26.8M
Chemistry-Biology Interface Predoctoral Training Grant 2024-2029T32GM133395 · NIGMS · UNIVERSITY OF DELAWARE · PI Catherine Leimkuhler Grimes · 2019 to 2026
$3.7M
Unraveling fibrosis with dynamic microenvironments and molecular toolsDP2HL152424 · NHLBI · UNIVERSITY OF DELAWARE · PI KLOXIN, APRIL M · 2019 to 2019
$2.4M
NHLBI NIH HHS DP2 HL152424NIGMS NIH HHS P20 GM103446NIGMS NIH HHS P20 GM104316NIGMS NIH HHS T32 GM133395
6 · The paper itself

Abstract

Late recurrences of breast cancer are hypothesized to arise from disseminated tumor cells (DTCs) that reactivate after dormancy and occur most frequently with estrogen receptor-positive (ER

Indexed as

Breast NeoplasmsBone MarrowCell CommunicationCoculture TechniquesFemaleHumansSignal TransductionTumor Microenvironment

Identifiers

PMID36888709
PMCPMC9995072
OpenAlexW4323636777

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.