ArticleProceedings of the National Academy of Sciences of the United States of America2023
Shear rate sensitizes bacterial pathogens to H
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Review
- Orthogonal microfluidic approaches reveal force-enhanced migration of bacterial populations on surfaces.bioRxiv : the preprint server for biology · 2026Article
- Flow-driven delivery boosts antibiotic effectiveness by overwhelming bacterial defenses.bioRxiv : the preprint server for biology · 2026Article
- Detoxification of host-relevant HbioRxiv : the preprint server for biology · 2026Article
- Article
- Flow-induced bending of flagella restrictsmBio · 2026Article
- Adaptability ofCombinatorial chemistry & high throughput screening · 2026Article
- Bacteria detect neutrophils via a system that responds to hypochlorous acid and flow.bioRxiv : the preprint server for biology · 2025Article
- The Barrier Properties of Biological Membranes Dictate How Cells Experience Oxidative Stress.Molecular microbiology · 2025Review
- Shear flow patterns antimicrobial gradients across bacterial populations.Science advances · 2025Article
- Bacterial species with different nanocolony morphologies have distinct flow-dependent colonization behaviors.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Combining multiple stressors blocks bacterial migration and growth.Current biology : CB · 2024Article
- Free-swimming bacteria transcriptionally respond to shear flow.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Collective peroxide detoxification determines microbial mutation rate plasticity in E. coli.PLoS biology · 2024Article
- Evidence and therapeutic implications of biomechanically regulated immunosurveillance in cancer and other diseases.Nature nanotechnology · 2024Review
- Characterization of the Entner-Doudoroff pathway inJournal of bacteriology · 2024Article
- Engineered bacteria titrate hydrogen sulfide and induce concentration-dependent effects on the host in a gut microphysiological system.Cell reports · 2023Article
- Genotoxic stress stimulates eDNA release via explosive cell lysis and thereby promotes streamer formation of Burkholderia cenocepacia H111 cultured in a microfluidic device.NPJ biofilms and microbiomes · 2023Article
- Characterization of the Entner-Douderoff Pathway inbioRxiv : the preprint server for biology · 2023Article
- Shear force enhances adhesion ofProceedings of the National Academy of Sciences of the United States of America · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Cells regularly experience fluid flow in natural systems. However, most experimental systems rely on batch cell culture and fail to consider the effect of flow-driven dynamics on cell physiology. Using microfluidics and single-cell imaging, we discover that the interplay of physical shear rate (a measure of fluid flow) and chemical stress trigger a transcriptional response in the human pathogen
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.