Evidence map›Paper›PMID 36888576›Full record

ArticlePloS one2023

Kazakh national dog breed Tazy: What do we know?

Anastassiya Perfilyeva, Kira Bespalova, Sergey Bespalov, Мamura Begmanova, Yelena Kuzovleva, Zhassulan Zhaniyazov, Olga Vishnyakova, Inna Nazarenko, Yuliya Perfilyeva, Ozada Khamdiyeva and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Anastassiya PerfilyevaDepartment of Molecular Genetics, Institute of Genetics and Physiology, Almaty, Kazakhstan.
Kira BespalovaDepartment of Molecular Genetics, Institute of Genetics and Physiology, Almaty, Kazakhstan.ORCID 0000-0001-8031-447X
Sergey BespalovDepartment of Theriology, Institute of Zoology, Almaty, Kazakhstan.
Мamura BegmanovaDepartment of Molecular Genetics, Institute of Genetics and Physiology, Almaty, Kazakhstan.
Yelena KuzovlevaDepartment of Molecular Genetics, Institute of Genetics and Physiology, Almaty, Kazakhstan.
Zhassulan ZhaniyazovDepartment of Molecular Genetics, Institute of Genetics and Physiology, Almaty, Kazakhstan.
Olga VishnyakovaDepartment of Сynology, Republican Federation of Public Associations of Hunters and Hunting Societies "Kansonar", Almaty, Kazakhstan.
Inna NazarenkoDepartment of Сynology, Republican Federation of Public Associations of Hunters and Hunting Societies "Kansonar", Astana, Kazakhstan.
Yuliya PerfilyevaDepartment of Immunology, M.A. Aitkhozhin's Institute of Molecular Biology and Biochemistry, Almaty, Kazakhstan.
Ozada KhamdiyevaDepartment of Molecular Genetics, Institute of Genetics and Physiology, Almaty, Kazakhstan.ORCID 0000-0002-3990-4512
Bakhytzhan BekmanovDepartment of Molecular Genetics, Institute of Genetics and Physiology, Almaty, Kazakhstan.
Institute of Plant Biology and Biotechnology · KZAl-Farabi Kazakh National University · KZHuntington's Disease Association · GBInstitute of Zoology · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Tazy or Kazakh National sighthound has been officially recognized as the national heritage of Kazakhstan. Comprehensive genetic studies of genetic diversity and population structure that could be used for selection and conservation of this unique dog breed have not been conducted so far. The aim of this study was to determine the genetic structure of the Tazy using microsatellite and SNP markers and to place the breed in the context of the world sighthound breeds. Our results showed that all 19 microsatellite loci examined were polymorphic. The observed number of alleles in the Tazy population varied from 6 (INU030 locus) to 12 (AHT137, REN169D01, AHTh260, AHT121, and FH2054 loci) with a mean of 9.778 alleles per locus. The mean number of effective alleles was 4.869 and ranged from 3.349 f to 4.841. All markers were highly informative (PIC values greater than 0.5) and ranged from 0.543 (REN247M23 locus) to 0.865 (AHT121 locus). The observed and expected heterozygosities in a total population were 0.748 and 0.769 and ranged from 0.746 to 0.750 and 0.656 to 0.769, respectively. Overall, the results confirmed that the Tazy breed has a high level of genetic diversity, no significant inbreeding, and a specific genetic structure. Three gene pools underlie the genetic diversity of the Tazy breed. SNP analysis using the CanineHD SNP array, which contains more than 170,000 SNP markers, showed that the Tazy breed is distinct from other sighthound breeds and genetically related to ancient eastern sighthound breeds sharing the same branch with the Afghan Hound and the Saluki. The results, together with archeological findings, confirm the ancient origin of the breed. The findings can be used for the conservation and international registration of the Tazy dog breed.

Indexed as

Genetic VariationInbreedingAllelesAnimalsDogsGene PoolHeterozygoteMicrosatellite Repeats

Identifiers

PMID36888576
PMCPMC9994743
OpenAlexW4323532941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.