Evidence map›Paper›PMID 36884204›Full record

SynthesisJournal of robotic surgery2023

Comparison between robot-assisted versus open nephroureterectomy for upper tract urothelial carcinoma: outcomes from a pooled analysis.

Kun-Peng Li, Si-Yu Chen, Chen-Yang Wang, Shun Wan, Li Yang

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of robotic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kun-Peng Li *Department of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Si-Yu Chen *Department of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Chen-Yang Wang *Department of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Shun WanDepartment of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Li YangDepartment of Urology, The Second Hospital of Lanzhou University, Lanzhou, China. ery_yangli@lzu.edu.cn.

Funding

Gansu Province Intellectual Property Planning project 21ZSCQ012Gansu Provincial Education Department outstanding graduate "innovation star" project 2021CXZX-154the regulatory mechanism of AMPK in ischemic-reperfusion injury and fibrosis in renal transplantation CY2015-YJRC08the Second Hospital of Lanzhou University "Cuiying Science and Technology Innovation" project CY2021-QN-A20
6 · The paper itself

Abstract

The present study aimed to compare the efficacy and safety between robot-assisted nephroureterectomy (RANU) and open nephroureterectomy (ONU) for the treatment of upper tract urothelial carcinoma (UTUC). We systematically searched four electronic databases (PubMed, Embase, Web of Science, and Cochrane Library) to locate pertinent studies published in English up to January 2023. The primary outcomes evaluated included perioperative results, complications, and oncologic outcomes. Statistical analyses and calculations were performed using Review Manager 5.4. The study was registered with PROSPERO (ID: CRD42022383035). In total, eight comparative trials, including 37,984 patients were enrolled. Compared to ONU, RANU was associated with a significantly shorter length of stay (weighted mean difference [WMD] - 1.63 days, 95% confidence interval [CI] - 2.90, - 0.35; p = 0.01), less blood loss (WMD - 107.04 mL, 95% CI - 204.97, - 9.11; p = 0.03), less major complication(OR 0.78, 95% CI 0.70, 0.88; p < 0.0001), and lower positive surgical margin (PSM) (OR 0.33, 95% CI 0.12, 0.92; p = 0.03). However, no statistically significant differences were observed between the two groups in operative time, transfusion rates, rate of lymph node dissection, lymph node yield, overall complications, overall survival, cancer-specific survival, recurrence-free survival, and progression-free survival. RANU has superior advantages compared to ONU in terms of length of hospital stay, blood loss, postoperative complications, and PSM, while providing comparable oncologic outcomes in patients with UTUC.

Indexed as

Carcinoma, Transitional CellRoboticsRobotic Surgical ProceduresUrinary Bladder NeoplasmsHumansNephroureterectomyTreatment OutcomeMeta-analysisOpen nephroureterectomyOutcomesRobot-assisted nephroureterectomyUpper tract urothelial carcinoma

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.