Evidence map›Paper›PMID 36883860›Full record

ArticleJournal of virology2023

Isolation of an Ecotropic Porcine Endogenous Retrovirus PERV-C from a Yucatan SLA

Michael Rodrigues Costa, Nicole Fischer, Antonia Gronewold, Barbara Gulich, Antonia W Godehardt, Ralf R Tönjes

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michael Rodrigues CostaDivision of Hematology, Cell and Gene Therapy, Paul-Ehrlich-Institut, Langen, Germany.
Nicole FischerDivision of Hematology, Cell and Gene Therapy, Paul-Ehrlich-Institut, Langen, Germany.
Antonia GronewoldDivision of Hematology, Cell and Gene Therapy, Paul-Ehrlich-Institut, Langen, Germany.
Barbara GulichDivision of Hematology, Cell and Gene Therapy, Paul-Ehrlich-Institut, Langen, Germany.
Antonia W GodehardtDivision of Hematology, Cell and Gene Therapy, Paul-Ehrlich-Institut, Langen, Germany.
Ralf R TönjesDivision of Hematology, Cell and Gene Therapy, Paul-Ehrlich-Institut, Langen, Germany.ORCID 0000-0001-8727-1935
Paul Ehrlich Institut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Xenotransplantation may compensate the limited number of human allografts for transplantation using pigs as organ donors. Porcine endogenous retroviruses inherit infectious potential if pig cells, tissues, or organs were transplanted to immunosuppressed human recipients. Particularly, ecotropic PERV-C that could recombine with PERV-A to highly replication-competent human-tropic PERV-A/C should be excluded from pig breeds designed for xenotransplantation. Because of their low proviral background, SLA

Indexed as

Endogenous RetrovirusesAnimalsHumansMexicoProvirusesSwineSwine, MiniatureTransplantation, HeterologousVirus ReplicationPERVSLAD/D haplotypeXenotransplantation

Identifiers

PMID36883860
PMCPMC10062142
OpenAlexW4323533984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.