Evidence map›Paper›PMID 36883818›Full record

ArticlemBio2023

Functional Dichotomy for a Hyphal Repressor in Candida albicans.

Yinhe Mao, Norma V Solis, Scott G Filler, Aaron P Mitchell

Open access · goldAbstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. International journal of molecular sciences · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Strain variation inmSphere · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Strain background ofMicrobiology (Reading, England) · 2024
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yinhe MaoDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.
Norma V SolisLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
Scott G FillerLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
Aaron P MitchellDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0002-0868-4000
University of Georgia · USUCLA Medical Center · USUniversity of California, Los Angeles · US

Funding

C. albicans invasion and proliferation during oral infectionR01DE026600 · NIDCR · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FILLER, SCOTT G, MITCHELL, AARON P · 2017 to 2021
$3.0M
Functional Analysis of Natural Variation in the Pathogen Candida albicansR01AI146103 · NIAID · UNIVERSITY OF GEORGIA · PI MITCHELL, AARON P · 2019 to 2023
$2.6M
NIAID NIH HHS 1R01AI146103NIAID NIH HHS R01 AI146103NIDCR NIH HHS R01 DE026600
6 · The paper itself

Abstract

Nrg1 is a repressor of hypha formation and hypha-associated gene expression in the fungal pathogen Candida albicans. It has been well studied in the genetic background of the type strain SC5314. Here, we tested Nrg1 function in four other diverse clinical isolates through an analysis of

Indexed as

Candida albicansHyphaeEndothelial CellsFungal ProteinsGene Expression Regulation, FungalFungal ProteinsCandida albicansgene regulationgeneticshyphal developmentnatural variation

Identifiers

PMID36883818
PMCPMC10127614
OpenAlexW4323534502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.