Evidence map›Paper›PMID 36883648›Full record

ArticleJournal of dental research2023

The Murine Oral Metatranscriptome Reveals Microbial and Host Signatures of Periodontal Disease.

S Joseph, M Carda-Diéguez, J Aduse-Opoku, A Alsam, A Mira, M A Curtis

Open access · hybridAbstract read
In one paragraph

Article in Journal of dental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Journal of oral microbiology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Multimodal inhibitory effect of matcha onMicrobiology spectrum · 2024
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

S JosephCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK.ORCID 0000-0002-0297-5405
M Carda-DiéguezOral Microbiome Lab, Department of Health and Genomics, FISABIO foundation, Valencia, Spain.
J Aduse-OpokuCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK.
A AlsamCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK.
A MiraOral Microbiome Lab, Department of Health and Genomics, FISABIO foundation, Valencia, Spain.
M A CurtisCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK.
King's College London · GBFundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana · ES

Funding

Medical Research Council MR/P012175/2
6 · The paper itself

Abstract

Periodontal disease is accompanied by alterations to cellular profiles and biological activities of both the subgingival microbiome and host tissues. Although significant progress has been made in describing the molecular basis of the homeostatic balance of host-commensal microbe interactions in health compared to the destructive imbalance in disease, particularly with respect to immune and inflammatory systems, few studies have attempted a comprehensive analysis in diverse host models. Here, we describe the development and application of a metatranscriptomic approach to analysis of host-microbe gene transcription in a murine periodontal disease model, based on oral gavage infection using

Indexed as

MicrobiotaPeriodontal DiseasesPorphyromonas gingivalisTranscriptomeAnimalsGene ExpressionMicebacterial metabolismdysbiosismetatranscriptomicsmouse modelsoral biofilmoral inflammationoral microbiomeperiodontitisP. gingivalis

Identifiers

PMID36883648
PMCPMC10152569
OpenAlexW4323531313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.