Evidence map›Paper›PMID 36883326›Full record

ArticleJournal of the American Chemical Society2023

Directed Biosynthesis of Mitragynine Stereoisomers.

Carsten Schotte, Yindi Jiang, Dagny Grzech, Thu-Thuy T Dang, Larissa C Laforest, Francisco León, Marco Mottinelli, Satya Swathi Nadakuduti, Christopher R McCurdy, Sarah E O'Connor

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Review
  3. Discovery of a Plant Pictet-Spenglerase With R-Stereoselectivity.Angewandte Chemie (International ed. in English) · 2026
    Article
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  17. Article
  18. Review
  19. Review
  20. Biosynthetic Origin of the Methoxy Group in Quinine and Related Alkaloids.Angewandte Chemie (International ed. in English) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Carsten SchotteDepartment of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, 07745 Jena, Germany.
Yindi JiangDepartment of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, 07745 Jena, Germany.
Dagny GrzechDepartment of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, 07745 Jena, Germany.ORCID 0000-0001-5575-2582
Thu-Thuy T DangDepartment of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, 07745 Jena, Germany.ORCID 0000-0002-6459-3664
Larissa C LaforestPlant Molecular and Cell Biology Program, University of Florida, Gainesville, Florida 32606, United States.
Francisco LeónDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.ORCID 0000-0002-5064-2381
Marco MottinelliDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.ORCID 0000-0001-5725-0439
Satya Swathi NadakudutiPlant Molecular and Cell Biology Program, University of Florida, Gainesville, Florida 32606, United States.ORCID 0000-0002-0831-3760
Christopher R McCurdyDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.ORCID 0000-0001-8695-2915
Sarah E O'ConnorDepartment of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, 07745 Jena, Germany.ORCID 0000-0003-0356-6213
Max Planck Institute for Chemical Ecology · DEUniversity of Florida · US

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Opioid use disorders: UF Pharmacy medications discovery and developmentUG3DA048353 · NIDA · UNIVERSITY OF FLORIDA · PI MCCURDY, CHRISTOPHER R, MCMAHON, LANCE R. · 2019 to 2020
$3.6M
Kratom alkaloids: in vitro and in vivo pharmacological mechanismsR01DA047855 · NIDA · UNIVERSITY OF FLORIDA · PI MCCURDY, CHRISTOPHER R, MCMAHON, LANCE R. · 2019 to 2023
$3.6M
NCATS NIH HHS UL1 TR001427NIDA NIH HHS R01 DA047855NIDA NIH HHS UG3 DA048353
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MitragynaSecologanin Tryptamine AlkaloidsMonoterpenesStereoisomerismmitragynineMonoterpenesSecologanin Tryptamine Alkaloids

Identifiers

PMID36883326
PMCPMC9999412
OpenAlexW4321493853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.