Evidence map›Paper›PMID 36883262›Full record

ArticleJournal of the American Geriatrics Society2023

Development and validation of the fall-related injury risk in nursing homes (INJURE-NH) prediction tool.

Matthew S Duprey, Andrew R Zullo, Natalia A Gouskova, Yoojin Lee, Alyssa Capuano, Douglas P Kiel, Lori A Daiello, Dae Hyun Kim, Sarah D Berry

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Interventions for preventing falls in older people in care facilities.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Matthew S DupreyDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID 0000-0002-2365-431X
Andrew R ZulloDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID 0000-0003-1673-4570
Natalia A GouskovaHinda and Arthur Marcus Institute for Aging Research, Hebrew Senior Life, Roslindale, Massachusetts, USA.
Yoojin LeeDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA.
Alyssa CapuanoDepartment of Pharmacy, Lifespan Rhode Island Hospital, Providence, Rhode Island, USA.
Douglas P KielHinda and Arthur Marcus Institute for Aging Research, Hebrew Senior Life, Roslindale, Massachusetts, USA.
Lori A DaielloDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA.
Dae Hyun KimHinda and Arthur Marcus Institute for Aging Research, Hebrew Senior Life, Roslindale, Massachusetts, USA.ORCID 0000-0001-7290-6838
Sarah D BerryHinda and Arthur Marcus Institute for Aging Research, Hebrew Senior Life, Roslindale, Massachusetts, USA.
Beth Israel Deaconess Medical Center · USBrown University · USHebrew SeniorLife · USRhode Island Hospital · USUniversity of Kentucky · US

Funding

Tracking and Evaluation CoreU54GM115677 · NIGMS · BROWN UNIVERSITY · PI KOGUT, STEPHEN J · 2016 to 2025
$45.0M
Safe Cardiometabolic Drug Prescribing to Prevent Injury in Nursing Home ResidentsRF1AG061221 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI BERRY, SARAH DYER · 2019 to 2019
$2.8M
Medications and the Risk of Motor Vehicle Crashes in Older AdultsR01AG065722 · NIA · BROWN UNIVERSITY · PI ZULLO, ANDREW REIS · 2020 to 2023
$2.1M
Mentoring Patient-Oriented Research to Prevent Injury in Older AdultsK24AG070106 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI Sarah Dyer Berry · 2021 to 2026
$735k
Opioid use in post-acute hip fracture care: prescribing patterns, effectiveness, and safetyR21AG061632 · NIA · BROWN UNIVERSITY · PI BEAUDOIN, FRANCESCA, ZULLO, ANDREW REIS · 2019 to 2020
$462k
NIA NIH HHS K24 AG070106NIA NIH HHS R01 AG065722NIA NIH HHS R21 AG061632NIA NIH HHS RF1 AG061221NIGMS NIH HHS U54 GM115677
6 · The paper itself

Abstract

backgroundExisting models to predict fall-related injuries (FRI) in nursing homes (NH) focus on hip fractures, yet hip fractures comprise less than half of all FRIs. We developed and validated a series of models to predict the absolute risk of FRIs in NH residents.

methodsRetrospective cohort study of long-stay US NH residents (≥100 days in the same facility) between January 1, 2016 and December 31, 2017 (n = 733,427) using Medicare claims and Minimum Data Set v3.0 clinical assessments. Predictors of FRIs were selected through LASSO logistic regression in a 2/3 random derivation sample and tested in a 1/3 validation sample. Sub-distribution hazard ratios (HR) and 95% confidence intervals (95% CI) were estimated for 6-month and 2-year follow-up. Discrimination was evaluated via C-statistic, and calibration compared the predicted rate of FRI to the observed rate. To develop a parsimonious clinical tool, we calculated a score using the five strongest predictors in the Fine-Gray model. Model performance was repeated in the validation sample.

resultsMean (Q1, Q3) age was 85.0 (77.5, 90.6) years and 69.6% were women. Within 2 years of follow-up, 43,976 (6.0%) residents experienced ≥1 FRI. Seventy predictors were included in the model. The discrimination of the 2-year prediction model was good (C-index = 0.70), and the calibration was excellent. Calibration and discrimination of the 6-month model were similar (C-index = 0.71). In the clinical tool to predict 2-year risk, the five characteristics included independence in activities of daily living (ADLs) (HR 2.27; 95% CI 2.14-2.41) and a history of non-hip fracture (HR 2.02; 95% CI 1.94-2.12). Performance results were similar in the validation sample.

conclusionsWe developed and validated a series of risk prediction models that can identify NH residents at greatest risk for FRI. In NH, these models should help target preventive strategies.

Indexed as

Hip FracturesAccidental FallsActivities of Daily LivingAgedFemaleHumansMaleMedicareNursing HomesRetrospective StudiesUnited Statesfall-related injuriesfracturefunctional assessmentlong-term carerisk prediction

Identifiers

PMID36883262
PMCPMC10258142
OpenAlexW4323533529

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.