Evidence map›Paper›PMID 36883180›Full record

ArticleBiophysics2022

High Dose Inhalation with Gaseous Nitric Oxide in COVID-19 Treatment.

E V Pechyonkin, A V Kovrizhkin, A V Pekshev, A B Vagapov, N A Sharapov, A F Vanin

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

E V PechyonkinStavropol State Medical University, 355017 Stavropol, Russia.
A V KovrizhkinCity Clinical Hospital no. 3, 355029 Stavropol, Russia.
A V PekshevBauman Moscow State Technical University, 105005 Moscow, Russia.
A B VagapovBauman Moscow State Technical University, 105005 Moscow, Russia.
N A SharapovBauman Moscow State Technical University, 105005 Moscow, Russia.
A F VaninSemenov Federal Research Center for Chemical Physics Russian Academy of Sciences, 119334 Moscow, Russia.
Bauman Moscow State Technical University · RUSemenov Institute of Chemical Physics · RUStavropol Regional Clinical Oncology Center · RUStavropol State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A method of treatment of a new coronavirus infection COVID-19 in patients undergoing high flow oxygenation is proposed and technically implemented; the method is based on high-dose inhalation of gaseous nitric oxide (NO) with the patient's spontaneous breathing. The results of the treatment of this disease demonstrating the high efficiency of the new method are presented. A possible mechanism of the blocking effect of high doses of inhaled nitric oxide on the replication of the SARS-CoV-2 virus is discussed; it is based on the formation of dinitrosyl iron complexes in the respiratory tract and lungs of COVID-19 patients with thiol-containing ligands acting as donors of NO and nitrosonium NO

Indexed as

COVID-19dinitrosyl iron complexesinhalationnitric oxidePLASONSARS-CoV-2

Identifiers

PMID36883180
PMCPMC9984126
OpenAlexW4323060257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.