Evidence map›Paper›PMID 36883070›Full record

ReviewInternational journal of nanomedicine2023

How Effective are Metal Nanotherapeutic Platforms Against Bacterial Infections? A Comprehensive Review of Literature.

Ying Li, Xiaomin Xia, Wenxue Hou, Hanlin Lv, Jie Liu, Xue Li

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 55 citations in OpenAlex.

  1. The Immunostimulatory Effect of MIL-101(Al)-NHInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Microparticles Loaded withPharmaceuticals (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Structural Analysis of CuACS omega · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ying Li *Department of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, People's Republic of China.
Xiaomin Xia *Department of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, People's Republic of China.
Wenxue HouDepartment of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, People's Republic of China.
Hanlin LvDepartment of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, People's Republic of China.
Jie LiuDepartment of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, People's Republic of China.
Xue LiDepartment of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, People's Republic of China.ORCID 0000-0001-7559-9554
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of multidrug-resistant bacteria has been deemed a global crisis that affects humans worldwide. Novel anti-infection strategies are desperately needed because of the limitations of conventional antibiotics. However, the increasing gap between clinical demand and antimicrobial treatment innovation, as well as the membrane permeability obstacle especially in gram-negative bacteria fearfully restrict the reformation of antibacterial strategy. Metal-organic frameworks (MOFs) have the advantages of adjustable apertures, high drug-loading rates, tailorable structures, and superior biocompatibilities, enabling their utilization as drug delivery carriers in biotherapy applications. Additionally, the metal elements in MOFs are usually bactericidal. This article provides a review of the state-of-The-art design, the underlying antibacterial mechanisms and antibacterial applications of MOF- and MOF-based drug-loading materials. In addition, the existing problems and future perspectives of MOF- and MOF-based drug-loading materials are also discussed.

Indexed as

Bacterial InfectionsMetal-Organic FrameworksAnti-Bacterial AgentsCell Membrane PermeabilityDrug CarriersDrug Delivery SystemsHumansMetalsAnti-Bacterial AgentsDrug CarriersMetal-Organic FrameworksMetalsantibacterialapplicationmechanismMOFnanomaterial

Identifiers

PMID36883070
PMCPMC9985878
OpenAlexW4322743020

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.