Evidence map›Paper›PMID 36882861›Full record

ReviewGut pathogens2023

In-silico computational approaches to study microbiota impacts on diseases and pharmacotherapy.

Hassan Shokri Garjan, Yadollah Omidi, Mehdi Poursheikhali Asghari, Reza Ferdousi

Abstract readReview
In one paragraph

Review in Gut pathogens, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hassan Shokri GarjanDepartment of Health Information Technology, School of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran.
Yadollah OmidiDepartment of Pharmaceutical Sciences, Nova Southeastern University, College of Pharmacy, Fort Lauderdale, FL, USA.
Mehdi Poursheikhali AsghariBiotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Reza FerdousiDepartment of Health Information Technology, School of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran. ferdousi.r@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microorganisms have been linked to a variety of critical human disease, thanks to advances in sequencing technology and microbiology. The growing recognition of human microbe-disease relationships provides crucial insights into the underlying disease process from the perspective of pathogens, which is extremely useful for pathogenesis research, early diagnosis, and precision medicine and therapy. Microbe-based analysis in terms of diseases and related drug discovery can predict new connections/mechanisms and provide new concepts. These phenomena have been studied via various in-silico computational approaches. This review aims to elaborate on the computational works conducted on the microbe-disease and microbe-drug topics, discuss the computational model approaches used for predicting associations and provide comprehensive information on the related databases. Finally, we discussed potential prospects and obstacles in this field of study, while also outlining some recommendations for further enhancing predictive capabilities.

Indexed as

Microbe–disease associationsMicrobe–disease predictionMicrobe–disease similarityMicrobiomeMicrobiotaSimilarity calculation method

Identifiers

PMID36882861
PMCPMC9990230

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.