Evidence map›Paper›PMID 36882835›Full record

ReviewMolecular cancer2023

The epigenetic regulatory mechanism of PIWI/piRNAs in human cancers.

Qun Zhang, Yazhi Zhu, Xinyu Cao, Wenhui Tan, Jianglong Yu, Yaqiong Lu, Ran Kang, Xiaolan Wang, Ermao Li

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecular cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 77 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Qun Zhang *Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Yazhi Zhu *Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Xinyu Cao *Chuanshan College University of South China, Hengyang, 421001, Hunan, China.
Wenhui TanHengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Jianglong YuHengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Yaqiong LuHengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Ran KangDepartment of Urology, Hengyang Medical School, The First Affiliated Hospital, University of South China, Hengyang, 421001, Hunan, China.
Xiaolan WangDepartment of Reproductive Medicine, Hengyang Medical School, The First Affiliated Hospital, University of South China, Hengyang, 421001, Hunan, China.
Ermao LiInstitute of Translational Medicine, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China. bailang74624@163.com.
University of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PIWI proteins have a strong correlation with PIWI-interacting RNAs (piRNAs), which are significant in development and reproduction of organisms. Recently, emerging evidences have indicated that apart from the reproductive function, PIWI/piRNAs with abnormal expression, also involve greatly in varieties of human cancers. Moreover, human PIWI proteins are usually expressed only in germ cells and hardly in somatic cells, so the abnormal expression of PIWI proteins in different types of cancer offer a promising opportunity for precision medicine. In this review, we discussed current researches about the biogenesis of piRNA, its epigenetic regulatory mechanisms in human cancers, such as N6-methyladenosine (m

Indexed as

NeoplasmsPiwi-Interacting RNADNA MethylationEpigenesis, GeneticHumansRNA InterferencePiwi-Interacting RNADNA methylationHistone modificationm6A methylationpiRNAPIWI protein

Identifiers

PMID36882835
PMCPMC9990219
OpenAlexW4323364088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.