Evidence map›Paper›PMID 36882804›Full record

Trial reportBMC musculoskeletal disorders2023

Effect of platelet-rich plasma versus steroid injection in plantar fasciitis: a randomized clinical trial.

Rachit Sharma, Narendra Kumar Chaudhary, Mandeep Karki, Dev Ram Sunuwar, Devendra Raj Singh, Pranil Man Singh Pradhan, Prakash Gyawali, Sailendra Kumar Duwal Shrestha, Kailash Kumar Bhandari

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC musculoskeletal disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04985396 (Effect of Platelet Rich Plasma Injection Compared With Steroid Injection for the Treatment of Plantar Fasciitis), which is not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04985396 nacompletednot on this map

Effect of Platelet Rich Plasma Injection Compared With Steroid Injection for the Treatment of Plantar Fasciitis: A Randomized Clinical Trial

TypeinterventionalSponsorArmed Police Force Hospital, NepalRan2021 to 2022Enrolled78ConditionsPlantar Fasciitis, Steroid, Platelet-rich Plasma (PRP)ArmsPlatelet Rich Plasma (PRP) group
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  6. Review
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  8. Article
  9. Response to Letter to the Editor: Ultrasound-guided injections for plantar fasciitis.Turkish journal of physical medicine and rehabilitation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Rachit Sharma *Nepal Orthopaedic Hospital, Kathmandu, Nepal.
Narendra Kumar Chaudhary *Nepal Orthopaedic Hospital, Kathmandu, Nepal. mscnarendra2019@gmail.com.
Mandeep KarkiNepal Orthopaedic Hospital, Kathmandu, Nepal.
Dev Ram SunuwarDepartment of Nutrition and Dietetics, Nepal Armed Police Force Hospital, Kathmandu, Nepal.
Devendra Raj SinghSchool of Human and Health Sciences, University of Huddersfield, Huddersfield, UK.
Pranil Man Singh PradhanDepartment of Community Medicine and Public Health, Institute of Medicine, Tribhuvan University, Tribhuvan, Nepal.
Prakash GyawaliNepal Orthopaedic Hospital, Kathmandu, Nepal.
Sailendra Kumar Duwal ShresthaDepartment of Orthopaedics, Nepal Armed Police Force Hospital, Kathmandu, Nepal.
Kailash Kumar BhandariNepal Orthopaedic Hospital, Kathmandu, Nepal.
Nepal Orthopaedic HospitalTribhuvan University · NPUniversity of Huddersfield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlantar fasciitis (PF) is a common orthopaedic problem, with heel pain worsening the quality of life. Although steroid injection is often used if the conservative treatment fails, Platelet-Rich Plasma (PRP) injection is gaining popularity due to its safety and long-lasting effect. However, the effect of PRP versus steroid injection in PF has not been studied yet in Nepal. Therefore, this study aimed to assess the effect of PRP compared with steroid injection in the treatment of PF.

methodsThis study was a single-center, hospital-based, open-label, parallel-group randomized clinical trial to compare the effect of PRP injection with steroid injection in plantar fasciitis between August 2020 and March 2022. A total of 90 randomly selected participants aged 18 to 60 years suffering from plantar fasciitis with failed conservative treatment were intervened. The American Orthopaedic Foot and Ankle Society (AOFAS) and the Visual Analog Scale (VAS) scoring system were used to evaluate functional mobility and pain before and after the intervention for three and six months, respectively. Statistical analyses were performed using a Student's two-sample t-test. P-value < 0.05 was considered statistically significant.

resultsThe PRP injection showed a better outcome than the steroid injection in six months follow-up. The mean (± SD) VAS score was significantly decreased in the PRP group (1.97 + 1.13) than in the steroid group (2.71 ± 0.94) with the group difference of -0.73 (95% CI: -1.18 to -0.28) at six months. Similarly, there was a significant increase in the AOFAS scores in the PRP group (86.04 ± 7.45) compared to the steroid group (81.23 ± 9.60) at six months of follow-up with a group difference of 4.80 (95% CI: 1.15 to 8.45). There was also a significant reduction of plantar fascia thickness in the PRP group compared to that of the steroid group (3.53 ± 0.81 versus 4.58 ± 1.02) at six months of follow-up with the group difference of -1.04 (95% CI: -1.44 to -0.65).

conclusionThe PRP injection showed better outcomes than steroid injection in plantar fasciitis treatment over the course of six months. Further research with a larger population and longer follow-up than six months is needed to generalize the findings and their long-term efficacy.

trial registrationNCT04985396. First registered on 02 August 2021. ( https://clinicaltrials.gov/ct2/show/NCT04985396 ).

Indexed as

Fasciitis, PlantarPlatelet-Rich PlasmaBehavior TherapyHumansPainQuality of LifePlantar fasciaPlantar fasciitisPlatelet-rich plasmaSteroid

Identifiers

PMID36882804
PMCPMC9989576
OpenAlexW4323361567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.