Evidence map›Paper›PMID 36882585›Full record

ArticlePediatric surgery international2023

Testicular descent revisited: a micro-computed tomography study in fetal rats.

Moritz Markel, Nicole Peukert, Marco Ginzel, Rainer Haak, Steffi Mayer, Martin Lacher, Dietrich Kluth, Jan-Hendrik Gosemann

Abstract read
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In one paragraph

Article in Pediatric surgery international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Editorial Comment: Testicular descent revisited: a microcomputed tomography study in fetal rats.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Moritz MarkelDepartment of Pediatric Surgery, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany. moritz.markel@web.de.
Nicole PeukertDepartment of Pediatric Surgery, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany.
Marco GinzelDepartment of Pediatric and Adolescent Surgery, Paracelsus Medical University Hospital, Salzburg, Austria.
Rainer HaakDepartment of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany.
Steffi MayerDepartment of Pediatric Surgery, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany.
Martin LacherDepartment of Pediatric Surgery, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany.
Dietrich KluthDepartment of Pediatric Surgery, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany.
Jan-Hendrik GosemannDepartment of Pediatric Surgery, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany.
Leipzig University · DEParacelsus Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is a long history of research dealing with the embryology of the testicular descent. However, important aspects like the role of the gubernaculum and the development of the processus vaginalis peritonei are not understood. Micro-computed tomography (µCT) is an established tool for anatomical studies in rodents. Our study applied µCT imaging to visualize the testicular descent in rats and focused on the role of the gubernacular bulb and the development of the processus vaginalis peritonei.

methodsRats from embryonic day 15 (ED15) to ED21 and newborns (N0) were fixed and dried using the "critical point" technique. We ran a SkyScan

resultsµCT imaging confirmed the intraperitoneal location of the testicles from ED15 to N0. The components of the inner genital moved closer together while the intestinal volume expanded. The gubernacular bulb seemed to be involved in the formation of the processus vaginalis peritonei.

conclusionHere, we utilized µCT imaging to visualize the testicular descent in the rat. Imaging provides new morphologic aspects on the development of the processus vaginalis peritonei.

Indexed as

GenitaliaTestisAnimalsFemaleHumansMalePregnancyPrenatal CareRatsX-Ray MicrotomographyGubernaculum testisMicro-CTPrenatal ratsTesticular descentTesticular development

Identifiers

PMID36882585
OpenAlexW4323349572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.