Evidence map›Paper›PMID 36882475›Full record

ArticleScientific reports2023

Automatic comprehensive aspects reports in clinical acute stroke MRIs.

Chin-Fu Liu, Jintong Li, Ganghyun Kim, Michael I Miller, Argye E Hillis, Andreia V Faria

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Predictive analysis in acute ischemic stroke imaging.Annals of medicine and surgery (2012) · 2026
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chin-Fu LiuCenter for Imaging Science, Johns Hopkins University, Baltimore, MD, USA.
Jintong LiDepartment of Physics, Johns Hopkins University, Baltimore, MD, USA.
Ganghyun KimDepartment of Neuroscience, Johns Hopkins University, Baltimore, MD, USA.
Michael I MillerCenter for Imaging Science, Johns Hopkins University, Baltimore, MD, USA.
Argye E HillisDepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Andreia V FariaDepartment of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. afaria1@jhmi.edu.

Funding

Telerehab for Aphasia (TERRA)P50DC014664 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI HICKOK, GREGORY · 2016 to 2025
$25.0M
Neural Basis of Lexical Deficits in Hyperacute StrokeR01DC005375 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI Argye E. Hillis · 2002 to 2026
$11.8M
TRD 4: Platforms for multi-modal and multi-scale imaging dataP41EB031771 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Hanzhang Lu, Peter CM Van Zijl · 2021 to 2026
$9.9M
The Neural Basis of Impaired Affective Prosody in Alzheimer's Disease and Frontotemporal DegenerationR01DC015466 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI HILLIS, ARGYE E. · 2017 to 2021
$3.5M
NIBIB NIH HHS P41 EB031771NIDCD NIH HHS P50 DC014664NIDCD NIH HHS R01 DC005375NIDCD NIH HHS R01 DC015466NIDCD NIH HHS R01 DC05375
6 · The paper itself

Abstract

The Alberta Stroke Program Early CT Score (ASPECTS) is a simple visual system to assess the extent and location of ischemic stroke core. The capability of ASPECTS for selecting patients' treatment, however, is affected by the variability in human evaluation. In this study, we developed a fully automatic system to calculate ASPECTS comparable with consensus expert readings. Our system was trained in 400 clinical diffusion weighted images of patients with acute infarcts and evaluated with an external testing set of 100 cases. The models are interpretable, and the results are comprehensive, evidencing the features that lead to the classification. This system adds to our automated pipeline for acute stroke detection, segmentation, and quantification in MRIs (ADS), which outputs digital infarct masks and the proportion of diverse brain regions injured, in addition to the predicted ASPECTS, the prediction probability and the explanatory features. ADS is public, free, accessible to non-experts, has very few computational requirements, and run in real time in local CPUs with a single command line, fulfilling the conditions to perform large-scale, reproducible clinical and translational research.

Indexed as

Ischemic StrokeStrokeAlbertaConsensusDiffusionHumans

Identifiers

PMID36882475
PMCPMC9992659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.