Evidence map›Paper›PMID 36882410›Full record

ArticleSignal transduction and targeted therapy2023

CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes.

Qiong Yuan, Yunwei Sun, Fan Yang, Dan Yan, Meihua Shen, Zhigang Jin, Lin Zhan, Guangqi Liu, Ling Yang, Qianyi Zhou and 8 more

Open access · goldAbstract read
In one paragraph

Article in Signal transduction and targeted therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
16.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 106 citations in OpenAlex.

  1. Review
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  3. The dark genome in cardiovascular medicine.European heart journal · 2026
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Qiong Yuan *Department of Cardiology, the Affiliated Hospital of Southwest Medical University and Key Laboratory of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research and Institute of Metabolic Diseases, Southwest Medical University, Luzhou, 646000, China.ORCID 0000-0001-9036-071X
Yunwei Sun *College of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Fan Yang *Department of Emergency and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China.
Dan YanCollege of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Meihua ShenCollege of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Zhigang JinChina Resource & WISCO General Hospital, Wuhan University of Science and Technology, Wuhan, 430065, China.
Lin ZhanCollege of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Guangqi LiuCollege of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Ling YangCollege of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Qianyi ZhouCollege of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Zhijun YuCollege of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Xiangyu ZhouDepartment of Cardiology, the Affiliated Hospital of Southwest Medical University and Key Laboratory of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research and Institute of Metabolic Diseases, Southwest Medical University, Luzhou, 646000, China.
Yang YuDepartment of Cardiology, the Affiliated Hospital of Southwest Medical University and Key Laboratory of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research and Institute of Metabolic Diseases, Southwest Medical University, Luzhou, 646000, China.
Yong XuDepartment of Cardiology, the Affiliated Hospital of Southwest Medical University and Key Laboratory of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research and Institute of Metabolic Diseases, Southwest Medical University, Luzhou, 646000, China.
Qingming WuCollege of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Jianfang LuoDepartment of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong General Hospital, Guangzhou, China.
Xiamin HuCollege of Pharmacy, Shanghai University of Medicine and Health Sciences, Shanghai, 210000, China. huxiaming@163.com.
Chunxiang ZhangDepartment of Cardiology, the Affiliated Hospital of Southwest Medical University and Key Laboratory of Medical Electrophysiology, Ministry of Education, Institute of Cardiovascular Research and Institute of Metabolic Diseases, Southwest Medical University, Luzhou, 646000, China. zhangchx999@163.com.
Wuhan University of Science and Technology · CNAffiliated Hospital of Southwest Medical University · CNGuangdong Academy of Medical Sciences · CNGuangdong General Hospital · CNShanghai University of Medicine and Health Sciences · CNSouthwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we identified that a conserved circular RNA (circRNA) DICAR, which was downregulated in diabetic mouse hearts. DICAR had an inhibitory effect on diabetic cardiomyopathy (DCM), as the spontaneous cardiac dysfunction, cardiac cell hypertrophy, and cardiac fibrosis occurred in DICAR deficiency (DICAR

Indexed as

Diabetes MellitusDiabetic CardiomyopathiesRNA, CircularAnimalsMiceMyocytes, CardiacPyroptosisTranscription FactorsRNA, CircularTranscription Factors

Identifiers

PMID36882410
PMCPMC9992392
OpenAlexW4323535544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.