Evidence map›Paper›PMID 36882231›Full record

ArticleBMJ paediatrics open2023

Paediatric admissions with SARS-CoV-2 during the Delta and Omicron waves: an Australian single-centre retrospective study.

Daryl R Cheng, Silja Schrader, Alissa McMinn, Nigel W Crawford, Shidan Tosif, Sarah Mcnab, Andrew C Steer

Abstract read
In one paragraph

Article in BMJ paediatrics open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daryl R ChengDepartment of General Medicine, Royal Children's Hospital Melbourne, Parkville, Victoria, Australia daryl.cheng@rch.org.au.ORCID 0000-0001-5455-957X
Silja SchraderSAEFVIC, Infection and Immunity, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Alissa McMinnSAEFVIC, Infection and Immunity, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Nigel W CrawfordDepartment of General Medicine, Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.
Shidan TosifDepartment of General Medicine, Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.
Sarah McnabDepartment of General Medicine, Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.
Andrew C SteerDepartment of Paediatrics, University of Melbourne, Parkville, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe clinical course of Australian children admitted to hospital with COVID-19 infection is not well understood, particularly over the Omicron period.

methodsThis study describes paediatric admissions to a single tertiary paediatric institution through the Delta and Omicron variant waves. All children admitted from 1 June 2021 to 30 September 2022 with a diagnosis of COVID-19 infection were included for analysis.

results117 patients were admitted during the Delta wave compared with 737 during the Omicron wave. The median length of stay was 3.3 days (IQR 1.7-6.75.1) during Delta, compared with 2.1 days (IQR 1.1-4.53.4) during Omicron (p<0.01). 83 patients (9.7%) required intensive care unit (ICU) admission, a greater proportion during Delta (20, 17.1%) than Omicron (63, 8.6%, p<0.01). Patients admitted to the ICU were less likely to have received a dose of COVID-19 vaccination prior to admission than patients admitted to the ward (8, 24.2% vs 154, 45.8%, p=0.028).

conclusionThe Omicron wave resulted in an absolute increase in the number of children compared with Delta, but cases had lower severity, demonstrated by shorter length of stay and a smaller proportion of patients requiring intensive care. This is consistent with US and UK data describing a similar pattern.

Indexed as

COVID-19SARS-CoV-2AustraliaChildCOVID-19 VaccinesHumansRetrospective StudiesCOVID-19 VaccinesCOVID-19virology

Identifiers

PMID36882231
PMCPMC10008196

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.