Evidence map›Paper›PMID 36882131›Full record

ReviewVirus research2023

Can egg yolk antibodies terminate the CSBV infection in apiculture?

Aifang Li, Qianfang Wang, Yu Huang, Lina Hu, Shuxuan Li, Qianqian Wang, Yangfan Yu, Haizhou Zhang, Doris Ying Ying Tang, Pau Loke Show and 1 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Virus research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Aifang LiMedical College, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China.
Qianfang WangSchool of Basic Medical Sciences, Henan University of Science and Technology, Luoyang, Henan 471023, China.
Yu HuangMedical College, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China.
Lina HuMedical College, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China.
Shuxuan LiMedical College, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China.
Qianqian WangMedical College, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China.
Yangfan YuMedical College, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China.
Haizhou ZhangLuoyang Fengzaokang Biotechnological Co. Ltd., Luoyang, Henan 471000, China.
Doris Ying Ying TangDepartment of Chemical and Environmental Engineering, Faculty of Science and Engineering, University of Nottingham Malaysia, Semenyih, Selangor Darul Ehsan 43500, Malaysia.
Pau Loke ShowDepartment of Chemical and Environmental Engineering, Faculty of Science and Engineering, University of Nottingham Malaysia, Semenyih, Selangor Darul Ehsan 43500, Malaysia; Zhejiang Provincial Key Laboratory for Subtropical Water Environment and Marine Biological Resources Protection, Wenzhou University, Wenzhou 325035, China; Department of Sustainable Engineering, Saveetha School of Engineering, SIMATS, Chennai 602105, India. Electronic address: PauLoke.Show@nottingham.edu.my.
Shuying FengMedical College, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China; Luoyang Fengzaokang Biotechnological Co. Ltd., Luoyang, Henan 471000, China. Electronic address: fsy@hactcm.edu.cn.
First Affiliated Hospital of Henan University · CNHenan University of Science and Technology · CNLuoyang Institute of Science and Technology · CNUniversity of Nottingham Malaysia Campus · MYWenzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chinese sacbrood virus (CSBV) is the most severe pathogen of Apis cerana, which leads to serious fatal diseases in bee colonies and eventual catastrophe for the Chinese beekeeping industry. Additionally, CSBV can potentially infect Apis mellifera by bridging the species barrier and significantly affect the productivity of the honey industry. Although several approaches, such as feeding royal jelly, traditional Chinese medicine, and double-stranded RNA treatments, have been employed to suppress CSBV infection, their practical applicabilities are constrained due to their poor effectiveness. In recent years, specific egg yolk antibodies (EYA) have been increasingly utilized in passive immunotherapy for infectious diseases without any side effects. According to both laboratory research and practical use, EYA have demonstrated superior protection for bees against CSBV infection. This review provided an in-depth analysis of the issues and drawbacks in this field in addition to provide a thorough summary of current advancements in CSBV studies. Some promising strategies for the synergistic study of EYA against CSBV, including the exploitation of novel antibody drugs, novel TCM monomer/formula determination, and development of nucleotide drugs, are also proposed in this review. Furthermore, the prospects for the future perspectives of EYA research and applications are presented. Collectively, EYA would terminate CSBV infection soon, as well as will provide scientific guidance and references to control and manage other viral infections in apiculture.

Indexed as

RNA VirusesVirus DiseasesAnimalsBeekeepingBeesEgg YolkApis ceranaCSBVEgg yolk antibodiesPrevention and treatmentSynergism

Identifiers

PMID36882131
PMCPMC10194372
OpenAlexW4323305626

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.