ArticleProceedings of the National Academy of Sciences of the United States of America2023
Darwinian evolution as a dynamical principle.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- A niche construction-based approach to evolution by natural selection without reproduction-proof of concept and implications.Royal Society open science · 2026Article
- Gut microbiota drives structural variation of exogenous probiotics to enhance colonization.Gut microbes · 2025Article
- Exploring interspecific interaction variability in microbiota: A review.Engineering microbiology · 2024Review
- Human and bats genome robustness under COSMIC mutational signatures.bioRxiv : the preprint server for biology · 2024Article
- Origins of Life: The Protein Folding Problem all over again?Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The prebiotic emergence of biological evolution.Royal Society open science · 2024Article
- On the Emergence of Autonomous Chemical Systems through Dissipation Kinetics.Life (Basel, Switzerland) · 2023Article
- Origins of life: first came evolutionary dynamics.QRB discovery · 2023Review
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2 authors.
Funding
Abstract
Darwinian evolution (DE)-biology's powerful process of adaptation-is remarkably different from other known dynamical processes. It is antithermodynamic, driving away from equilibrium; it has persisted for 3.5 billion years; and its target, fitness, can seem like "Just So" stories. For insights, we make a computational model. In the Darwinian Evolution Machine (DEM) model, resource-driven duplication and competition operate inside a cycle of search/compete/choose. We find the following: 1) DE requires multiorganism coexistence for its long-term persistence and ability to cross fitness valleys. 2) DE is driven by resource dynamics, like booms and busts, not just by mutational change. And, 3) fitness ratcheting requires a mechanistic separation between variation and selection steps, perhaps explaining biology's use of separate polymers, DNA and proteins.
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