Evidence map›Paper›PMID 36881454›Full record

ArticleJMIR research protocols2023

Health System-Level Barriers to Living Donor Kidney Transplantation: Protocol for a Comparative Case Study Analysis.

Anna Horton, Katya Loban, Peter Nugus, Marie-Chantal Fortin, Lakshman Gunaratnam, Greg Knoll, Istvan Mucsi, Prosanto Chaudhury, David Landsberg, Michel Paquet and 2 more

Open access · goldFull text read
In one paragraph

Article in JMIR research protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Anna HortonResearch Institute of the McGill University Health Centre, Montreal, QC, Canada.ORCID https://orcid.org/0000-0002-8168-2108
Katya LobanResearch Institute of the McGill University Health Centre, Montreal, QC, Canada.ORCID https://orcid.org/0000-0003-3691-1319
Peter NugusDepartment of Family Medicine and the Institute of Health Sciences Education, McGill University, Montreal, QC, Canada.ORCID https://orcid.org/0000-0001-6426-0125
Marie-Chantal FortinCentre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, QC, Canada.ORCID https://orcid.org/0000-0002-8437-0556
Lakshman GunaratnamMatthew Mailing Centre for Translational Transplant Studies, Lawson Health Research Institute, London Health Sciences Centre, London, ON, Canada.ORCID https://orcid.org/0000-0002-8845-1126
Greg KnollDivision of Nephrology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.ORCID https://orcid.org/0000-0001-5442-9310
Istvan MucsiAjmera Transplant Center and Division of Nephrology, University Health Network, Toronto, ON, Canada.ORCID https://orcid.org/0000-0002-4781-4699
Prosanto ChaudhuryResearch Institute of the McGill University Health Centre, Montreal, QC, Canada.ORCID https://orcid.org/0000-0002-3461-4620
David LandsbergDepartment of Medicine, University of British Columbia, Vancouver, BC, Canada.ORCID https://orcid.org/0000-0003-1151-0658
Michel PaquetCentre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, QC, Canada.ORCID https://orcid.org/0000-0002-0606-617X
Marcelo CantarovichResearch Institute of the McGill University Health Centre, Montreal, QC, Canada.ORCID https://orcid.org/0000-0002-4766-3333
Shaifali SandalResearch Institute of the McGill University Health Centre, Montreal, QC, Canada.ORCID https://orcid.org/0000-0003-1941-0598
McGill University Health Centre · CACentre Hospitalier de l’Université de Montréal · CAMcGill University · CAUniversity Health Network · CAUniversity of British Columbia · CAUniversity of Ottawa · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiving donor kidney transplantation (LDKT) is the best treatment option for patients with kidney failure and offers significant medical and economic advantages for both patients and health systems. Despite this, rates of LDKT in Canada have stagnated and vary significantly across Canadian provinces, the reasons for which are not well understood. Our prior work has suggested that system-level factors may be contributing to these differences. Identifying these factors can help inform system-level interventions to increase LDKT.

objectiveOur objective is to generate a systemic interpretation of LDKT delivery across provincial health systems with variable performance. We aim to identify the attributes and processes that facilitate the delivery of LDKT to patients, and those that create barriers and compare these across systems with variable performance. These objectives are contextualized within our broader goal of increasing rates of LDKT in Canada, particularly in lower-performing provinces.

methodsThis research takes the form of a qualitative comparative case study analysis of 3 provincial health systems in Canada that have high, moderate, and low rates of LDKT performance (the percentage of LDKT to all kidney transplantations performed). Our approach is underpinned by an understanding of health systems as complex adaptive systems that are multilevel and interconnected, and involve nonlinear interactions between people and organizations, operating within a loosely bounded network. Data collection will comprise semistructured interviews, document reviews, and focus groups. Individual case studies will be conducted and analyzed using inductive thematic analysis. Following this, our comparative analysis will operationalize resource-based theory to compare case study data and generate explanations for our research question.

resultsThis project was funded from 2020 to 2023. Individual case studies were carried out between November 2020 and August 2022. The comparative case analysis will begin in December 2022 and is expected to conclude in April 2023. Submission of the publication is projected for June 2023.

conclusionsBy investigating health systems as complex adaptive systems and making comparisons across provinces, this study will identify how health systems can improve the delivery of LDKT to patients with kidney failure. Our resource-based theory framework will provide a granular analysis of the attributes and processes that facilitate or create barriers to LDKT delivery across multiple organizations and levels of practice. Our findings will have practice and policy implications and help inform transferrable competencies and system-level interventions conducive to increasing LDKT. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/44172.

Indexed as

barrierscomplex adaptive systemshealth systemsliving donor kidney transplantationresource based theorytransplantation

Identifiers

PMID36881454
PMCPMC10031444
OpenAlexW4317931862

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read12
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.