Observational studyTranslational vision science & technology2023
Semi-Automated Analysis of Foveal Maturity in Premature and Full-Term Infants Using Handheld Swept-Source Optical Coherence Tomography.
Observational study in Translational vision science & technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Assessing visual and refractive outcomes of subretinal fluid detected by handheld swept-source optical coherence tomography in full-term newborns.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2026Article
- Validating DevCheck: a semi-automated computer algorithm for measuring foveal immaturity in premature infants.Quantitative imaging in medicine and surgery · 2026Article
- Ocular fundus and optical coherence tomography (OCT) findings in children prenatally exposed to opioid maintenance therapy (OMT).BMC ophthalmology · 2025Article
- Comparison of Retinal and Choroidal OCT Measures and Features at Term Equivalent Age in Preterm and Term Infants.Investigative ophthalmology & visual science · 2025Article
- New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025Review
- Semi-Automated Analysis of Dome-Shaped Macula in Preterm and Full-Term Infants Using Handheld Swept-Source Optical Coherence Tomography.Investigative ophthalmology & visual science · 2024Observational
- Assessing spectral effectiveness in color fundus photography for deep learning classification of retinopathy of prematurity.Journal of biomedical optics · 2024Article
- Vitreoretinal biomarkers of retinopathy of prematurity using handheld optical coherence tomography: a review.Frontiers in pediatrics · 2023Review
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To develop a semi-automated method of measuring foveal maturity using investigational handheld swept source-optical coherence tomography (SS-OCT). Methods: In this prospective, observational study, full-term newborns and preterm infants undergoing routine retinopathy of prematurity screening were imaged. Semi-automated analysis measured foveal angle and chorioretinal thicknesses at the central fovea and average two-sided parafovea by three-grader consensus, correlating with OCT features and demographics. Results: One hundred ninety-four imaging sessions from 70 infants were included (47.8% girls, 37.6 ± 3.4 weeks postmenstrual age, 26 preterm infants with birth weight 1057 ± 325.0, gestational age 29.0 ± 3.0 weeks). Foveal angle (96.1 ± 22.0 degrees) steepened with increasing birth weight (P = 0.003), decreasing inner retinal layer thickness, and increasing gestational age, postmenstrual age, and foveal and parafoveal choroidal thickness (all P < 0.001). Inner retinal fovea/parafovea ratio (0.4 ± 0.2) correlated with increasing inner foveal layers, decreasing postmenstrual age, gestational age, and birth weight (all P < 0.001). Outer retinal F/P ratio (0.7 ± 0.2) correlated with ellipsoid zone presence (P < 0.001), increased gestational age (P = 0.002), and birth weight (P = 0.003). Foveal (447.8 ± 120.6 microns) and parafoveal (420.9 ± 109.2) choroidal thicknesses correlated with foveal ellipsoid zone presence (P = 0.007 and P = 0.01, respectively), postmenstrual age, birth weight, gestational age, and decreasing inner retinal layers (all P < 0.001). Conclusions: Foveal development is dynamic and partially observed through semi-automated analysis of handheld SS-OCT imaging. Translational Relevance: Semi-automated analysis of SS-OCT images can identify measures of foveal maturity.
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