Evidence map›Paper›PMID 36881372›Full record

SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2023

Is There a Role for Mechanical and Oral Antibiotic Bowel Preparation for Patients Undergoing Minimally Invasive Colorectal Surgery? A Systematic Review and Meta-analysis.

Mohamed Maatouk, Alaa Akid, Ghassen Hamdi Kbir, Aymen Mabrouk, Marwen Selmi, Anis Ben Dhaou, Sami Daldoul, Karim Haouet, Mounir Ben Moussa

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mohamed MaatoukA21 Surgery Department, Charles Nicolle Hospital, Research Laboratory LR12ES01, Faculty of Medicine of Tunis, Tunis El Manar University, Rue 9 Avril - 1007 Bab Saadoun, Tunis, Tunisia. maatouk.m@yahoo.com.ORCID 0000-0002-2892-7225
Alaa AkidFaculty of Medicine of Monastir, Monastir University, Monastir, Tunisia.
Ghassen Hamdi KbirA21 Surgery Department, Charles Nicolle Hospital, Research Laboratory LR12ES01, Faculty of Medicine of Tunis, Tunis El Manar University, Rue 9 Avril - 1007 Bab Saadoun, Tunis, Tunisia.
Aymen MabroukA21 Surgery Department, Charles Nicolle Hospital, Research Laboratory LR12ES01, Faculty of Medicine of Tunis, Tunis El Manar University, Rue 9 Avril - 1007 Bab Saadoun, Tunis, Tunisia.
Marwen SelmiA21 Surgery Department, Charles Nicolle Hospital, Research Laboratory LR12ES01, Faculty of Medicine of Tunis, Tunis El Manar University, Rue 9 Avril - 1007 Bab Saadoun, Tunis, Tunisia.
Anis Ben DhaouA21 Surgery Department, Charles Nicolle Hospital, Research Laboratory LR12ES01, Faculty of Medicine of Tunis, Tunis El Manar University, Rue 9 Avril - 1007 Bab Saadoun, Tunis, Tunisia.
Sami DaldoulA21 Surgery Department, Charles Nicolle Hospital, Research Laboratory LR12ES01, Faculty of Medicine of Tunis, Tunis El Manar University, Rue 9 Avril - 1007 Bab Saadoun, Tunis, Tunisia.
Karim HaouetA21 Surgery Department, Charles Nicolle Hospital, Research Laboratory LR12ES01, Faculty of Medicine of Tunis, Tunis El Manar University, Rue 9 Avril - 1007 Bab Saadoun, Tunis, Tunisia.
Mounir Ben MoussaA21 Surgery Department, Charles Nicolle Hospital, Research Laboratory LR12ES01, Faculty of Medicine of Tunis, Tunis El Manar University, Rue 9 Avril - 1007 Bab Saadoun, Tunis, Tunisia.
Tunis El Manar University · TNUniversity of Monastir · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo date, all meta-analyses on oral antibiotic prophylaxis (OA) and mechanical bowel preparation (MBP) in colorectal surgery have included results of both open and minimally invasive approaches. Mixing both procedures may lead to false conclusions. The aim of the study was to assess the available evidence of mechanical and oral antibiotic bowel preparation in reducing the incidence of surgical site infection (SSI) and other complications following minimally invasive elective colorectal surgery.

methodsWe searched PubMed, Science Direct, Google Scholar and Cochrane Library from 2000 to May 1, 2022. Comparative randomized and non-randomized studies were included. We reviewed the use of oral OA, MBP and combinations of these treatments. The methodological quality of the included studies was assessed using the Rob v2 and Robins-I tools.

resultsWe included 18 studies (7 randomized controlled trials and 11 cohort studies). Meta-analysis of the included studies showed that the combination of MBP + OA was associated with a significant reduction in SSI, AL and overall morbidity compared with the other options no preparation, MBP only and OA only. 

conclusionAdding OA with MBP has a positive impact in reducing the incidence of SSI, AL and overall morbidity after minimally invasive colorectal surgery. Therefore, the combination of OA and MBP should be encouraged in this selected group of patients undergoing minimally invasive surgery.

Indexed as

Anti-Bacterial AgentsColorectal SurgeryAntibiotic ProphylaxisElective Surgical ProceduresHumansMinimally Invasive Surgical ProceduresPreoperative CareSurgical Wound InfectionAnti-Bacterial AgentsLaparascopicMechanical bowel preparationOral antibioticsRoboticSurgical site infection

Identifiers

PMID36881372
OpenAlexW4323347835

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.