Evidence map›Paper›PMID 36881315›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Analysis of Visual Recovery After Optic Nerve Crush in Adult Zebrafish.

An Beckers, Steven Bergmans, Annelies Van Dyck, Lieve Moons

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

An BeckersNeural Circuit Development and Regeneration Research Group, Animal Physiology and Neurobiology Section, Department of Biology, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
Steven BergmansNeural Circuit Development and Regeneration Research Group, Animal Physiology and Neurobiology Section, Department of Biology, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
Annelies Van DyckNeural Circuit Development and Regeneration Research Group, Animal Physiology and Neurobiology Section, Department of Biology, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
Lieve MoonsNeural Circuit Development and Regeneration Research Group, Animal Physiology and Neurobiology Section, Department of Biology, Leuven Brain Institute, KU Leuven, Leuven, Belgium. Lieve.moons@kuleuven.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zebrafish can successfully regenerate axons after optic nerve crush (ONC). Here, we describe two different behavioral tests to map visual recovery: the dorsal light reflex (DLR) test and the optokinetic response (OKR) test. The DLR is based on the tendency of fish to orient their back to a light source, and it can be tested by rotating a flashlight around the dorsolateral axis of the animal or by measuring the angle between the left/right body axis and the horizon. The OKR, in contrast, consists of reflexive eye movements triggered by motion in the visual field of the subject and is measured by placing the fish in a drum on which rotating black-and-white stripes are projected.

Indexed as

EyeZebrafishAnimalsAxonsMotionOptic NerveAxonal regenerationBehavioral testDorsal light reflexNeurobiologyOptic nerve crushOptokinetic responseRetinaRetinotectal systemVisual recoveryZebrafish

Identifiers

PMID36881315

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.