Evidence map›Paper›PMID 36881296›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Noncoding Regulatory RNAs: Isolation and Analysis of Neuronal Circular RNAs and MicroRNAs.

Michela Dell'Orco, Grigorios Papageorgiou, Nikolaos Mellios, Nora I Perrone-Bizzozero

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michela Dell'OrcoDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Grigorios PapageorgiouDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Nikolaos MelliosDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Nora I Perrone-BizzozeroDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA. nbizzozero@salud.unm.edu.
University of New Mexico · US

Funding

Unfolded Protein Response and Autophagy in T Helper Cell Effector FunctionP20GM121176 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI VOJO P DERETIC · 2017 to 2026
$24.9M
Competing roles of microRNAs and RNA-binding proteins in drug addictionR01DA034097 · NIDA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI NEISEWANDER, JANET L, PERRONE-BIZZOZERO, NORA IRMA · 2012 to 2016
$2.2M
Sex-dependent effects of prenatal alcohol exposure on developmental programmingR01AA026583 · NIAAA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI MELLIOS, NIKOLAOS · 2019 to 2023
$1.7M
Role of Psychiatric Disease-associated Circular RNAs in Neuronal Function and CognitionR56MH119150 · NIMH · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI MELLIOS, NIKOLAOS · 2019 to 2020
$732k
Role of circHomer1 in synaptic plasticity and cocaine-seeking behaviorR21DA048651 · NIDA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI NEISEWANDER, JANET L, PERRONE-BIZZOZERO, NORA IRMA · 2020 to 2021
$425k
NIAAA NIH HHS R01 AA026583NIDA NIH HHS R01 DA034097NIDA NIH HHS R21 DA048651NIGMS NIH HHS P20 GM121176NIMH NIH HHS R56 MH119150
6 · The paper itself

Abstract

In addition to expressing a large number of protein-coding transcripts, including alternatively spliced isoforms of the same mRNAs, neurons express a large number of noncoding RNAs. These include microRNAs (miRNAs), circular RNAs (circRNAs), and other regulatory RNAs. The isolation and quantitative analyses of diverse types of RNAs in neurons are critical to understand not only the posttranscriptional mechanisms regulating mRNA levels and their translation but also the potential of several RNAs expressed in the same neurons to regulate these processes by generating networks of competing endogenous RNAs (ceRNAs). This chapter will describe methods for the isolation and analyses of circRNA and miRNA levels from the same brain tissue sample.

Indexed as

MicroRNAsNeuronsRNA, CircularRNA, MessengerRNA, UntranslatedMicroRNAsRNA, CircularRNA, MessengerRNA, UntranslatedBrain tissuescircRNAsmiRNAsqRT-PCRRNA isolation

Identifiers

PMID36881296
OpenAlexW4323348167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.