ReviewCurrent neurology and neuroscience reports2023
Modern Sedation and Analgesia Strategies in Neurocritical Care.
Review in Current neurology and neuroscience reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06848452 (Clinical Study on the Efficacy and Safety of Hydromorphone for ICU Analgesia), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Study on the Efficacy and Safety of Hydromorphone for ICU Analgesia
Who cites it
15 citing papers in PubMed.
- Long-Term Sedation Effect of Cipepofol Compared to Dexmedetomidine in Patients Receiving Invasive Mechanical Ventilation: A Multicenter, Randomized, Open-Label, Parallel-Controlled Study.Advances in therapy · 2026Trial
- Early inhaled isoflurane sedation in neurocritical patients with invasive intracranial pressure monitoring: the NEURO-CONDA randomized pilot trial.Critical care (London, England) · 2026Trial
- Initial sedation strategy and clinical outcomes in mechanically ventilated neurocritical care patients with acute brain injury: a retrospective cohort study.Frontiers in medicine · 2026Article
- Sedation and analgesia strategies in the neuro intensive care unit.World journal of critical care medicine · 2025Review
- Delirium as a mediating factor in the survival benefits of dexmedetomidine in acute brain injury management.Scientific reports · 2025Article
- Article
- Isoflurane vs. Propofol Sedation in Patients with Severe Stroke: A Clinical Proof-of-Concept-Study.Journal of clinical medicine · 2025Article
- Development and Validation of a Neuro-Intensive Care Protocol for Traumatic Brain Injury Management.Cureus · 2025Article
- Passive head-up tilt positioning as an early mobilization strategy in neurocritical care: a prospective-retrospective controlled study.Frontiers in neurology · 2025Article
- Pharmacological mechanism and clinical application of ciprofol.Frontiers in pharmacology · 2025Review
- Managing Intracranial Pressure Crisis.Current neurology and neuroscience reports · 2024Review
- Sedation Vacations in Neurocritical Care: Friend or Foe?Current neurology and neuroscience reports · 2024Review
- Dexmedetomidine improves clinical outcomes in sepsis-induced myocardial injury: a retrospective cohort study.Frontiers in pharmacology · 2024Article
- Disturbed laterality of non-rapid eye movement sleep oscillations in post-stroke human sleep: a pilot study.medRxiv : the preprint server for health sciences · 2023Article
- Disturbed laterality of non-rapid eye movement sleep oscillations in post-stroke human sleep: a pilot study.Frontiers in neurology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewPatients with acute neurologic injury require a specialized approach to critical care, particularly with regard to sedation and analgesia. This article reviews the most recent advances in methodology, pharmacology, and best practices of sedation and analgesia for the neurocritical care population. RECENT
findingsIn addition to established agents such as propofol and midazolam, dexmedetomidine and ketamine are two sedative agents that play an increasingly central role, as they have a favorable side effect profile on cerebral hemodynamics and rapid offset can facilitate repeated neurologic exams. Recent evidence suggests that dexmedetomidine is also an effective component when managing delirium. Combined analgo-sedation with low doses of short-acting opiates is a preferred sedation strategy to facilitate neurologic exams as well as patient-ventilator synchrony. Optimal care for patients in the neurocritical care population requires an adaptation of general ICU strategies that incorporates understanding of neurophysiology and the need for close neuromonitoring. Recent data continues to improve care tailored to this population.
Indexed as
Identifiers
36881257What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.