Evidence map›Paper›PMID 36881112›Full record

ReviewDer Nervenarzt2023

[Brain health services: individual dementia risk profiling at the Cologne Alzheimer Prevention Center].

Philip Zeyen, Lena Sannemann, Lara Bohr, Claus Escher, Theresa Müller, Alfredo Ramírez, Ayda Rostamzadeh, Frank Jessen

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Nervenarzt, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Philip ZeyenMedizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland. philip.zeyen@uk-koeln.de.
Lena SannemannMedizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland. lena.sannemann@uk-koeln.de.
Lara BohrMedizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Claus EscherKlinik für Neurodegenerative Erkrankungen und Gerontopsychiatrie, Universitätsklinikum Bonn, Bonn, Deutschland.
Theresa MüllerMedizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Alfredo RamírezMedizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Ayda RostamzadehMedizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Frank JessenMedizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccording to current knowledge approximately 30-40% of all cases of dementia can be attributed to modifiable risk factors. As a result, dementia prevention and the concept of brain health are becoming increasingly relevant. RESEARCH QUESTION: The requirements for brain health services and their implementation are discussed and the Cologne Alzheimer Prevention Center (KAP) of the University Hospital Cologne is described as an example. MATERIAL AND

methodsIn addition to a report on international brain health initiatives, the main activities of the KAP are presented. A program for individual risk profiling and risk communication is provided, which was piloted in the KAP in the context of the "Individual risk profiling for Alzheimer's disease and dementia prevention (INSPIRATION)" study. The prevalence of risk factors in a cognitively healthy sample aged 50-86 years (n = 162) with interest in dementia prevention is presented.

resultsThe most common risk factors were non-Mediterranean diet, obesity, subjective poor sleep quality and increased stress. Based on these results, preventive interventions can be developed that are adapted to the individual risk profile as a personalized medicine approach. DISCUSSION: Structures such as the KAP can provide individual risk factor assessment and personalized dementia prevention. The efficacy of this approach on dementia risk reduction needs to be evaluated.

Indexed as

Alzheimer DiseaseDementiaBrainHealth ServicesHumansRisk FactorsAlzheimer’s diseaseDementiaPreventionRisk communicationRisk factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.