Evidence map›Paper›PMID 36881093›Full record

ArticleIn vivo (Athens, Greece)

Encephalitis Associated With SARS-CoV-2 Infection in a Child With Chiari Malformation Type I.

José Manuel Reyes-Ruiz, Claudia Manrique-Calvillo, Gustavo Martínez-Mier, Arturo Osvaldo Servin-Monroy, Gilraed Mota-García, Flor DE Maria Lugo-Miranda, Enrique Villegas-Del Angel, Paola Zarate-Segura, Fernando Bastida-Gonzalez, Rosa Maria Del Angel

Open access · diamondAbstract readCase Reports
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. COVID-19: a multi-organ perspective.Frontiers in cellular and infection microbiology · 2024
    Review
  3. Observational
  4. Letter to the Editor: RE: Reyes-RuizIn vivo (Athens, Greece)
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

José Manuel Reyes-RuizUnidad Médica de Alta Especialidad, Hospital de Especialidades No. 14, Centro Médico Nacional "Adolfo Ruiz Cortines", Instituto Mexicano del Seguro Social (IMSS), Veracruz, Mexico.
Claudia Manrique-CalvilloDepartamento de Pediatria, Centro Médico Ecatepec del Instituto de Seguridad Social del Estado de México y Municipios (ISSEMyM), Ecatepec de Morelos, Mexico.
Gustavo Martínez-MierUnidad Médica de Alta Especialidad, Hospital de Especialidades No. 14, Centro Médico Nacional "Adolfo Ruiz Cortines", Instituto Mexicano del Seguro Social (IMSS), Veracruz, Mexico.
Arturo Osvaldo Servin-MonroyDepartamento de Epidemiología, Instituto de Seguridad Social del Estado de México y Municipios (ISSEMyM), Toluca de Lerdo, Mexico.
Gilraed Mota-GarcíaUnidad Médica de Alta Especialidad, Hospital de Especialidades No. 14, Centro Médico Nacional "Adolfo Ruiz Cortines", Instituto Mexicano del Seguro Social (IMSS), Veracruz, Mexico.
Flor DE Maria Lugo-MirandaUnidad de Medicina Preventiva y Vigilancia Epidemiológica, Centro Médico Ecatepec del Instituto de Seguridad Social del Estado de México y Municipios (ISSEMyM), Ecatepec de Morelos, Mexico.
Enrique Villegas-Del AngelCentro Médico ABC, Mexico City, Mexico; rmangel@cinvestav.mx.
Paola Zarate-SeguraLaboratorio de Medicina Traslacional, Escuela Superior de Medicina, Instituto Politécnico Nacional (IPN), Mexico City, Mexico.
Fernando Bastida-GonzalezLaboratorio de Biología Molecular, Laboratorio Estatal de Salud Pública del Estado de México, Toluca de Lerdo, Mexico; mijomeil@hotmail.com.
Rosa Maria Del AngelDepartment of Infectomics and Molecular Pathogenesis, Center for Research and Advanced Studies (CINVESTAV-IPN), Mexico City, Mexico.
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MXHospital de Especialidades · MXInstituto de Salud del Estado de México · MXInstituto Politécnico Nacional · MXUniversidad Veracruzana · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThere is increasing evidence that patients infected with SARS-CoV-2 develop neurological manifestations such as encephalitis. The purpose of this article was to present a case of viral encephalitis associated with SARS-CoV-2 in a 14-year-old child with Chiari malformation type I. CASE REPORT: The patient manifested frontal headache, nausea, vomiting, skin pallor, right side Babinski sign and was diagnosed with Chiari malformation type I. He was admitted with generalized seizures and suspected encephalitis. Brain inflammation and viral RNA in the cerebrospinal fluid suggested SARS-CoV-2 encephalitis. These findings indicate that the SARS-CoV-2 test in CSF of patients with neurological manifestations, confusion, and fever during the COVID-19 pandemic should be carried out even when there is no evidence of respiratory infection. To our knowledge, this presentation of encephalitis associated with COVID-19 has not yet been reported in a patient with a congenital syndrome such as Chiari malformation type I.

conclusionFurther clinical data are needed to determine the complications of encephalitis due to SARS-CoV-2 in patients with Chiari malformation type I to standardize diagnosis and treatment.

Indexed as

Arnold-Chiari MalformationCOVID-19EncephalitisAdolescentChildHumansMalePandemicsSARS-CoV-2Chiari malformation type ICOVID-19encephalitisSARS-CoV-2

Identifiers

PMID36881093
PMCPMC10026637
OpenAlexW4323348147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.