Evidence map›Paper›PMID 36880961›Full record

ArticleJournal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research2023

A Novel Inactive Isoform with a Restored Reading Frame Is Expressed from the Human Interferon Lambda 4 TT Allele at rs368234815.

Seema Bharatiya, Aditya Agarwal, Sreedhar Chinnaswamy

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. The Interferon-Lambda Family Celebrates 20 Years of Scientific Discovery.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Seema BharatiyaInfectious Disease Genetics, National Institute of Biomedical Genomics, Kalyani, West Bengal, India.
Aditya AgarwalInfectious Disease Genetics, National Institute of Biomedical Genomics, Kalyani, West Bengal, India.
Sreedhar ChinnaswamyInfectious Disease Genetics, National Institute of Biomedical Genomics, Kalyani, West Bengal, India.ORCID 0000-0003-0095-3453
National Institute of Biomedical Genomics · INRegional Centre for Biotechnology · IN

Funding

DBT-Wellcome Trust India Alliance IA/I/17/1/503122
6 · The paper itself

Abstract

The TT allele of the dinucleotide variant rs368234815 (TT/ΔG) abolishes the open reading frame (ORF) created by the ancestral ΔG allele of the human interferon lambda 4 (

Indexed as

Interferon LambdaLeukocytes, MononuclearAllelesAntibodies, MonoclonalGenotypeHepacivirusHumansInterleukinsPolymorphism, Single NucleotideProtein IsoformsReading FramesAntibodies, MonoclonalIFNL4 protein, humanInterferon LambdaInterleukinsProtein IsoformsIFNL4IFN-λ4rs368234815splicing isoformstype III IFNs

Identifiers

PMID36880961
PMCPMC10517323
OpenAlexW4323347473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.