Evidence map›Paper›PMID 36880696›Full record

ArticleGenetics and molecular biology2023

Genome editing in maize: Toward improving complex traits in a global crop.

José Hernandes-Lopes, Juliana Erika de Carvalho Teixeira Yassitepe, Alessandra Koltun, Laurens Pauwels, Viviane Cristina Heinzen da Silva, Ricardo Augusto Dante, Isabel Rodrigues Gerhardt, Paulo Arruda

Abstract read
In one paragraph

Article in Genetics and molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Unlocking the potential of 'Egusi' melon (Frontiers in plant science · 2025
    Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

José Hernandes-LopesUniversidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.ORCID http://orcid.org/0000-0002-8169-5179
Juliana Erika de Carvalho Teixeira YassitepeUniversidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.ORCID http://orcid.org/0000-0002-6862-3031
Alessandra KoltunUniversidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.ORCID http://orcid.org/0000-0001-8889-5264
Laurens PauwelsGhent University, Department of Plant Biotechnology and Bioinformatics, Ghent, Belgium.ORCID http://orcid.org/0000-0002-0221-9052
Viviane Cristina Heinzen da SilvaUniversidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.
Ricardo Augusto DanteUniversidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.ORCID http://orcid.org/0000-0002-2738-4433
Isabel Rodrigues GerhardtUniversidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.ORCID http://orcid.org/0000-0003-1397-0199
Paulo ArrudaUniversidade Estadual de Campinas, Genomics for Climate Change Research Center (GCCRC), Campinas, SP, Brazil.ORCID http://orcid.org/0000-0002-8365-731X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in genome editing have enormously enhanced the effort to develop biotechnology crops for more sustainable food production. CRISPR/Cas, the most versatile genome-editing tool, has shown the potential to create genome modifications that range from gene knockout and gene expression pattern modulations to allele-specific changes in order to design superior genotypes harboring multiple improved agronomic traits. However, a frequent bottleneck is the delivery of CRISPR/Cas to crops that are less amenable to transformation and regeneration. Several technologies have recently been proposed to overcome transformation recalcitrance, including HI-Edit/IMGE and ectopic/transient expression of genes encoding morphogenic regulators. These technologies allow the eroding of the barriers that make crops inaccessible for genome editing. In this review, we discuss the advances in genome editing in crops with a particular focus on the use of technologies to improve complex traits such as water use efficiency, drought stress, and yield in maize.

Identifiers

PMID36880696
PMCPMC9990078

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.