Evidence map›Paper›PMID 36880419›Full record

ArticleThe Laryngoscope2023

Prognosis of Acute Low-Tone Hearing Loss Without Vertigo: A Scoping Review.

Ryan J Huang, Amanda Del Risco, Kristal M Riska, Matthew W Cooper, Nicholas W Clark, Samantha J Kaplan, David Kaylie, Howard W Francis

Open access · greenAbstract readScoping Review
In one paragraph

Article in The Laryngoscope, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. [Efficacy analysis of anti-migraine therapy for acute low-frequency hearing loss and investigation of its mechanisms].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ryan J HuangDepartment of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, North Carolina, U.S.A.ORCID 0000-0002-2155-6273
Amanda Del RiscoDepartment of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, North Carolina, U.S.A.
Kristal M RiskaDepartment of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, North Carolina, U.S.A.ORCID 0000-0001-8159-1962
Matthew W CooperDepartment of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, North Carolina, U.S.A.
Nicholas W ClarkDepartment of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, North Carolina, U.S.A.
Samantha J KaplanDuke Medical Center Library, Duke University School of Medicine, Durham, North Carolina, U.S.A.
David KaylieDepartment of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, North Carolina, U.S.A.
Howard W FrancisDepartment of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, North Carolina, U.S.A.
Duke University · US

Funding

Otolaryngology Surgeon- Scientist career Path (OSSP) programR25DC020172 · NIDCD · DUKE UNIVERSITY · PI Howard W Francis, Bradley J Goldstein · 2022 to 2026
$1.2M
NIDCD NIH HHS R25 DC020172
6 · The paper itself

Abstract

objectiveDespite its relatively high prevalence, our understanding of the natural clinical course of acute low-tone hearing loss (ALHL) without vertigo remains incomplete. The purpose of this study is to summarize the findings of studies that evaluated recovery from hearing loss (HL), recurrence and/or fluctuation of HL, and progression to Meniere's Disease (MD) of patients presenting with ALHL without vertigo.

methodsA scoping review of the English literature was performed. On May 14, 2020 and July 6, 2022, MEDLINE, Embase, and Scopus were searched to identify articles related to the prognosis of ALHL. To be included, articles had to present outcomes that were clearly distinguishable for patients with ALHL without vertigo. Two reviewers evaluated articles for inclusion and extracted data. Disagreements were adjudicated by a third reviewer.

resultsForty-one studies were included. There was extensive heterogeneity between studies in regard to defining ALHL, treatment methods, and time of follow-up. Most of the cohorts (39 out of 40) reported partial or complete recovery of hearing in the majority (>50%) of patients, although reports of recurrence were relatively common. Progression to MD was infrequently reported. Shorter time from onset of symptoms to treatment predicted better hearing outcomes in 6 of 8 studies.

conclusionThe literature suggests that although the majority of patients with ALHL experience hearing improvement, recurrence and/or fluctuation are common, and progression to MD occurs in a minority of patients. Additional trials utilizing standardized inclusion and outcome criteria are needed to determine the ideal treatment for ALHL. LEVEL OF EVIDENCE: NA Laryngoscope, 133:2457-2469, 2023.

Indexed as

DeafnessHearing LossHearing Loss, SensorineuralMeniere DiseaseHumansPrognosisVertigofluctuationhearing losslow-toneMeniere's diseaserecurrencetreatment

Identifiers

PMID36880419
PMCPMC10483019
OpenAlexW4323347303

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.