ArticlePlant physiology2023
Transcription factors MhDREB2A/MhZAT10 play a role in drought and cold stress response crosstalk in apple.
Article in Plant physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Regulatory insights underlying apple to cold stress.Horticulture research · 2026Article
- The Structure, Classification, Functional Diversity and Regulatory Mechanism of Plant C2H2 Transcription Factors.Biology · 2026Review
- From Shared Mechanisms to Precision Breeding: Engineering Cold and Drought Cross-Tolerance in Crops.International journal of molecular sciences · 2026Review
- MsDREB2A modulates alfalfa growth by regulating MsCRE1 involved in cytokinin biosynthesis.BMC plant biology · 2026Article
- Root-Specific Signal Modules Mediating Abiotic Stress Tolerance in Fruit Crops.Plants (Basel, Switzerland) · 2026Review
- Universal features of alternative splicing and the regulatory roles of transcription factors in this process under diverse environmental stimuli in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Chloroplast ATP-dependent metalloprotease FtsH5/VAR1 confers cold-stress tolerance through singlet oxygen and salicylic acid signaling.Plant communications · 2025Article
- Hierarchical Regulatory Networks Reveal Conserved Drivers of Plant Drought Response at the Cell-Type Level.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Evaluation of Salt Resistance of Six Apple Rootstocks.International journal of molecular sciences · 2024Article
- PlZAT10 binds to the ABA catabolism gene PlCYP707A2 promoter to mediate seed dormancy release in Paeonia lactiflora.Plant cell reports · 2024Article
- Genome-Wide Identification and Expression Analysis of the Cys2His2 Zinc Finger Protein Gene Family inJournal of fungi (Basel, Switzerland) · 2024Article
- Genome-Wide Characterization of IQD Family Proteins in Apple and Functional Analysis of the Microtubule-Regulating Abilities of MdIQD17 and MdIQD28 under Cold Stress.Plants (Basel, Switzerland) · 2024Article
- Abscisic acid regulates ClHorticulture research · 2024Article
- Research progress on the physiological response and molecular mechanism of cold response in plants.Frontiers in plant science · 2024Review
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- Insights into the molecular mechanisms underlying responses of apple trees to abiotic stresses.Horticulture research · 2023Article
- Focus on fruit crops.Plant physiology · 2023Article
- Deciphering the roles of unknown/uncharacterized genes in plant development and stress responses.Frontiers in plant science · 2023Review
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Drought and cold stresses seriously affect tree growth and fruit yield during apple (Malus domestica) production, with combined stress causing injury such as shoot shriveling. However, the molecular mechanism underlying crosstalk between responses to drought and cold stress remains to be clarified. In this study, we characterized the zinc finger transcription factor ZINC FINGER OF ARABIDOPSIS THALIANA 10 (ZAT10) through comparative analysis of shoot-shriveling tolerance between tolerant and sensitive apple rootstocks. MhZAT10 responded to both drought and cold stresses. Heterologous expression of MhZAT10 in the sensitive rootstock 'G935' from domesticated apple (Malus domestica) promoted shoot-shriveling tolerance, while silencing of MhZAT10 expression in the tolerant rootstock 'SH6' of Malus honanensis reduced stress tolerance. We determined that the apple transcription factor DEHYDRATION RESPONSE ELEMENT-BINDING PROTEIN 2A (DREB2A) is a direct regulator activating the expression of MhZAT10 in response to drought stress. Apple plants overexpressing both MhDREB2A and MhZAT10 genes exhibited enhanced tolerance to drought and cold stress, while plants overexpressing MhDREB2A but with silenced expression of MhZAT10 showed reduced tolerance, suggesting a critical role of MhDREB2A-MhZAT10 in the crosstalk between drought and cold stress responses. We further identified drought-tolerant MhWRKY31 and cold-tolerant MhMYB88 and MhMYB124 as downstream regulatory target genes of MhZAT10. Our findings reveal a MhDREB2A-MhZAT10 module involved in crosstalk between drought and cold stress responses, which may have applications in apple rootstock breeding programs aimed at developing shoot-shriveling tolerance.
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