ArticleCancer medicine2023
Association between rapid renal function deterioration and cancer mortality in the elderly: A retrospective cohort study.
Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Functional and Survival Outcomes of Partial Versus Radical Nephrectomy in Renal Cell Carcinoma Patients With Pre-Existing Chronic Kidney Disease: A Real-World Study.World journal of oncology · 2026Article
- Impact of Impaired Renal Function on the Efficacy and Safety of Second-Line Tyrosine Kinase Inhibitor Therapy After First-Line Immuno-Oncology Combination Therapy in Metastatic Renal Cell Carcinoma: A Japanese Multicenter Retrospective Study.International journal of urology : official journal of the Japanese Urological Association · 2025Article
- External validation and comparison of clinical prediction models for cisplatin-associated acute kidney injury: a single-centre retrospective study.Journal of pharmaceutical health care and sciences · 2025Article
- Association between changes of frailty status/frailty components status and rapid loss of kidney function in middle- aged and older populations.BMC nephrology · 2024Article
- Association between rapid renal function deterioration and cancer mortality in the elderly: A retrospective cohort study.Cancer medicine · 2023Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundKidney function is associated with clinical outcomes in patients with cancer.
objectivesThis study aimed to assess the association between kidney function decline and cancer-related mortality among community-dwelling elderly individuals.
designThis was a retrospective longitudinal cohort study.
participantsThe 61,988 participants were from an elderly health examination database in Taipei City from 2005 to 2012. MEASUREMENTS: Multivariable logistic regression was used to assess the association between baseline covariates and rapidly deteriorating estimated glomerular filtration rate (eGFR). In addition, Cox proportional hazards model and the Fine-Gray model were used to quantify the effects of covariates on total cancer mortality and six specific cancer mortalities.
resultsDuring the follow-up period, 1482 participants died of cancer. Their baseline average eGFR was 73.8 ± 19.9 mL/min/1.73 m
conclusionsElderly individuals with rapid kidney function decline had higher cancer mortality risks. Serial assessments of dynamic changes in eGFR might provide information relevant for cancer prognosis.
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