ReviewThe Japanese dental science review2023
Direct pulp capping procedures - Evidence and practice.
Review in The Japanese dental science review, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed.
- Clinical Evaluation of Three Direct Pulp Capping Materials in Caries-Induced Pulpitis of Mature Permanent Teeth: A Randomized Controlled Trial.Clinical and experimental dental research · 2026Trial
- Direct pulp capping versus partial pulpotomy using RetroMTABMC oral health · 2026Trial
- Short-term dentin-pulp complex repair with four pulp capping materials: a double-blind randomized crossover histological study.Scientific reports · 2025Trial
- Clinical and radiographic assessment of mineral trioxide aggregate with platelet rich fibrin as pulp capping biomaterials: a 12-month randomized trial.Scientific reports · 2025Trial
- Development of a Nano-Hybrid Composite Using Bovine Hydroxyapatite and Montmorillonite for Endodontic Applications-An In Vitro Study.International endodontic journal · 2026Article
- Ultrastructural Evaluation of Newly Formed Dentine After Direct Pulp Capping With Mineral Trioxide Aggregate and Calcium Hydroxide Using Focused Ion Beam Scanning Electron Microscopy and Stimulated Emission Depletion.International endodontic journal · 2026Article
- Clinical and radiographic outcomes of partial pulpotomy procedure in primary molars utilising different capping materials and different sealing methods: a randomised clinical trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Applications of Nanomaterials in Restorative Dentistry and Endodontics: A Narrative Review.Materials (Basel, Switzerland) · 2026Review
- Evaluation of dentin bridge formation and postoperative pain reduction after direct pulp capping using photobiomodulation therapy, platelet-rich fibrin, and mineral trioxide aggregate - A randomized clinical trial.Journal of conservative dentistry and endodontics · 2026Article
- Comparative Analysis of the Physical Properties of Three Different Tricalcium Silicate Cements: An In Vitro Study.European journal of dentistry · 2026Article
- Dose-dependent effects of Metformin on proliferation and odontogenic differentiation of dental pulp stem cells.BMC oral health · 2026Article
- Conservative treatment of a horizontal root fracture at the bone margin of a mandibular central incisor: a case report.Journal of medical case reports · 2026Article
- Histopathologic responses of the dental pulp to an experimental calcium aluminate-calcium silicate based capping material in comparison to mineral trioxide aggregate.Scientific reports · 2026Article
- Multifunctional bilayer scaffold for dental pulp protection and sustained calcium hydroxide release for mineralized tissue regeneration.Biomaterials · 2026Article
- Effect of combined application of premixed bioceramic paste and diode laser in vital pulp therapy: an immunohistochemical randomized controlled split-mouth in vivo animal experiment.Restorative dentistry & endodontics · 2026Article
- Novel Metformin-Encapsulating Poly(lactic-co-glycolic acid) Microspheres in Calcium Phosphate Pulp-Capping Cement with Dental Pulp Stem Cells for Regenerative Applications.Materials (Basel, Switzerland) · 2026Article
- Comparative evaluation of MTA and PRF for direct pulp capping in permanent mandibular molars - A randomized control trial.Bioinformation · 2026Article
- Antibiotic approaches to endodontic regeneration.Biomaterial investigations in dentistry · 2026Review
- Clinical Challenges and Therapeutic Approaches in Managing Deep Carious Lesions Close to the Pulp in Permanent Teeth: A Narrative Review.International journal of dentistry · 2026Review
- Diagnosis to Follow-Up: Practice Variability and Evidence-Based Gaps In Vital Pulp Therapy Among Saudi Dentists.Oral health & preventive dentistry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of direct pulp capping (DPC) is to promote pulp healing and mineralized tissue barrier formation by placing a dental biomaterial directly over the exposed pulp. Successful application of this approach avoids the need for further and more extensive treatment. In order to ensure a complete pulp healing with the placement of restorative materials, a mineralized tissue barrier must form to protect the pulp from microbial invasion. The formation of mineralized tissue barrier can only be induced when there is a significant reduction in pulp inflammation and infection. Consequently, promoting the healing of pulp inflammation may provide a favorable therapeutic opportunity to maintain the sustainability of DPC treatment. Mineralized tissue formation was observed as the favorable reaction of exposed pulp tissue against a variety of dental biomaterials utilized for DPC. This observation reveals an intrinsic capacity of pulp tissue for healing. Therefore, this review focuses on the DPC and its healing procedure as well as the materials used for DPC treatment and their mechanisms of action to promote pulpal healing. In addition, the factors that can affect the healing process of DPC, clinical considerations and future perspective has been described.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.