Evidence map›Paper›PMID 36879940›Full record

ArticleJournal of obstetrics and gynaecology of India2023

Evaluation Of Epidermal Growth Factor-Like Domain (EGFL7) mRNA Expression and its Protein Level in Preeclampsia.

Noha M Salah, Nora M Hussein, Souad M Aboazma, Hend A Shalaby, Amal K Seleem

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of obstetrics and gynaecology of India, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Noha M SalahMedical Biochemistry and Molecular Biology Faculty of Medicine, Mansoura University, El Gomhouria St, Mansoura, 35516 Dakahlia Governorate Egypt.ORCID 0000-0003-2711-2224
Nora M HusseinMedical Biochemistry and Molecular Biology Faculty of Medicine, Mansoura University, El Gomhouria St, Mansoura, 35516 Dakahlia Governorate Egypt.
Souad M AboazmaMedical Biochemistry and Molecular Biology Faculty of Medicine, Mansoura University, El Gomhouria St, Mansoura, 35516 Dakahlia Governorate Egypt.
Hend A ShalabyObstetrics and Gynecology Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Amal K SeleemMedical Biochemistry and Molecular Biology Faculty of Medicine, Mansoura University, El Gomhouria St, Mansoura, 35516 Dakahlia Governorate Egypt.
Mansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate the mRNA expression of epidermal growth factor-like domain 7 (EGFL7) in maternal blood and its protein level in sera of pregnant women complicated with preeclampsia (PE). Method: Case-control study involving 25 pregnant women diagnosed with PE (cases) and 25 gestational age-matched normal pregnant women (controls). EGFL7 mRNA expression in normal and PE patients was quantified by (qRT-PCR), and EGFL7 protein level was estimated using ELISA. Results: The RQ values of EGFL7 in the PE group were significantly higher than in the NC group ( Conclusion: EGFL7 mRNA is overexpressed in maternal blood of pregnancies complicated with preeclampsia. Serum EGFL7 protein is elevated in PE cases and can be used as a diagnostic marker for preeclampsia.

Indexed as

EGFL-7Epidermal growth factorGene expressionPreeclampsia

Identifiers

PMID36879940
PMCPMC9984659
OpenAlexW4306990564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.