Evidence map›Paper›PMID 36879929›Full record

ArticleJTO clinical and research reports2023

Osimertinib in NSCLC With Atypical

Jingran Ji, Jacqueline V Aredo, Andrew Piper-Vallillo, Laura Huppert, Julia K Rotow, Hatim Husain, Susan Stewart, Rosemary Cobb, Heather A Wakelee, Collin M Blakely and 8 more

Open access · goldAbstract read
In one paragraph

Article in JTO clinical and research reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. UncommonCurrent oncology (Toronto, Ont.) · 2022
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Amivantamab Plus Lazertinib in AtypicalJournal of clinical oncology : official journal of the American Society of Clinical Oncology · 2026
    Article
  9. Identifying the genomic landscape of EGFR-mutant lung cancers with central nervous system metastases.Annals of oncology : official journal of the European Society for Medical Oncology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Observational
  16. Article
  17. Osimertinib in uncommonTranslational lung cancer research · 2024
    Article
  18. Subtype of EGFR exon 19 deletion mutations.Translational lung cancer research · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 1 country.

Jingran JiCity of Hope Comprehensive Cancer Center, Duarte, California.
Jacqueline V AredoStanford Cancer Institute, Stanford, California.
Andrew Piper-VallilloMassachusetts General Hospital Cancer Center, Boston, Massachusetts.
Laura HuppertUCSF Helen Diller Comprehensive Cancer Center, San Francisco, California.
Julia K RotowDana-Farber Cancer Institute, Boston, Massachusetts.
Hatim HusainUCSD Moores Comprehensive Cancer Center, La Jolla, San Diego, California.
Susan StewartUC Davis Comprehensive Cancer Center, Sacramento, California.
Rosemary CobbMassachusetts General Hospital Cancer Center, Boston, Massachusetts.
Heather A WakeleeStanford Cancer Institute, Stanford, California.
Collin M BlakelyUCSF Helen Diller Comprehensive Cancer Center, San Francisco, California.
Melisa L WongUCSF Helen Diller Comprehensive Cancer Center, San Francisco, California.
Matthew A GubensUCSF Helen Diller Comprehensive Cancer Center, San Francisco, California.
Mohammad H MadaniUC Davis Comprehensive Cancer Center, Sacramento, California.
Subba R DigumarthyMassachusetts General Hospital Cancer Center, Boston, Massachusetts.
Caroline McCoachUCSF Helen Diller Comprehensive Cancer Center, San Francisco, California.
Zofia PiotrowskaMassachusetts General Hospital Cancer Center, Boston, Massachusetts.
Joel W NealStanford Cancer Institute, Stanford, California.
Jonathan W RiessUC Davis Comprehensive Cancer Center, Sacramento, California.
UCSF Helen Diller Family Comprehensive Cancer Center · USMassachusetts General Hospital · USUC Davis Comprehensive Cancer CenterCancer Prevention Institute of California · USDana-Farber Cancer Institute · USStanford Cancer InstituteUniversity of California, Davis · USUniversity of California, San Diego · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
NCI NIH HHS P30 CA093373
6 · The paper itself

Abstract

Introduction: Methods: Patients with metastatic NSCLC treated with osimertinib, harboring at least one atypical Results: A total of 50 patients with NSCLC with uncommon Conclusions: Osimertinib has activity in patients with NSCLC harboring atypical

Indexed as

Atypical EGFR mutationG719XL861QNon–small cell lung cancerOsimertinib

Identifiers

PMID36879929
PMCPMC9984841
OpenAlexW4313856913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.