Evidence map›Paper›PMID 36879901›Full record

ArticleNAR genomics and bioinformatics2023

Mhaned Oubounyt, Maria L Elkjaer, Tanja Laske, Alexander G B Grønning, Marcus J Moeller, Jan Baumbach

Abstract read
In one paragraph

Article in NAR genomics and bioinformatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mhaned OubounytInstitute for Computational Systems Biology, University of Hamburg, Hamburg, Germany.ORCID https://orcid.org/0000-0001-5011-6683
Maria L ElkjaerDepartment of Neurology, Odense University Hospital, Odense, Denmark.ORCID https://orcid.org/0000-0002-8596-142X
Tanja LaskeInstitute for Computational Systems Biology, University of Hamburg, Hamburg, Germany.ORCID https://orcid.org/0000-0002-7922-7595
Alexander G B GrønningNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Marcus J MoellerHeisenberg Chair of Preventive and Translational Nephrology, Department of Nephrology, Rheumatology and Clinical Immunology, RWTH Aachen University, Aachen, Germany.
Jan BaumbachInstitute for Computational Systems Biology, University of Hamburg, Hamburg, Germany.ORCID https://orcid.org/0000-0002-0282-0462

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-cell RNA sequencing (scRNA-seq) technology provides an unprecedented opportunity to understand gene functions and interactions at single-cell resolution. While computational tools for scRNA-seq data analysis to decipher differential gene expression profiles and differential pathway expression exist, we still lack methods to learn differential regulatory disease mechanisms directly from the single-cell data. Here, we provide a new methodology, named DiNiro, to unravel such mechanisms

Identifiers

PMID36879901
PMCPMC9985332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.