Evidence map›Paper›PMID 36879895›Full record

ArticleJournal of experimental pharmacology2023

Antipyretic Potential of 80% Methanol Extract and Solvent Fractions of

Bantayehu Addis Tegegne, Agumas Alemu Alehegn

Abstract read
In one paragraph

Article in Journal of experimental pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  3. Article
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  5. Article
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  7. Article
  8. Hepatoprotective Effect ofGlobal advances in integrative medicine and health
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bantayehu Addis TegegneDepartment of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.ORCID 0000-0002-6178-8335
Agumas Alemu AlehegnDepartment of Pharmacy, Lumame Primary Hospital, Lumame, Ethiopia.ORCID 0000-0001-5396-1735

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Since fever is a complicated physiological reaction to an infection or aseptic stimulus, finding safer solutions that are more potent and derived from plants is essential to resolving this issue. Objective: The present study aimed to assess the antipyretic potential of leaf extract and solvent fractions of Methods: The antipyretic activities of crude extract and solvent fractions of Results: The crude extract demonstrated significant antipyretic potential (P<0.05 by 100 mg/kg and 200 mg/kg as well as P<0.01 by 400 mg/kg), with a maximum of 95.06% reduction in rectal temperature at 400 mg/kg, comparable to 98.37% at 2.5 hours by the standard drug. Similarly, all doses of the aqueous fraction, as well as 200 mg/kg and 400 mg/kg doses of the ethyl acetate fractions, resulted in a significant (P<0.05) reduction in rectal temperature when compared to the corresponding value of the negative control group. Conclusion: Extracts of

Indexed as

antipyretic activityB. abyssinica leavesextractfractionyeast-induced pyrexia

Identifiers

PMID36879895
PMCPMC9985388

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.