Evidence map›Paper›PMID 36879572›Full record

ArticleArchives of rheumatology2022

MT-CO1 expression in nine organs and tissues of different-aged

Xinglan Huang, Peng Yan, Xinghua Song, Suiying Zhang, Yuqiong Deng, Caifeng Huang, Xiaoqing Zhao, Sheng Liu, Xiping Cheng, Dongjiang Liao

Open access · diamondAbstract read
In one paragraph

Article in Archives of rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xinglan HuangDepartment of Dermatology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.ORCID 0000-0002-6422-7875
Peng YanDepartment of Respiratory Medicine, State Key Laboratory of Respiratory Diseases, Guangzhou, China.ORCID 0000-0001-7030-0066
Xinghua SongThe First Affiliated Hospital of Guangzhou Medical University, Traditional Chinese Medicine, Guangzhou, China.ORCID 0000-0002-4236-3155
Suiying ZhangDepartment of Dermatology, Dongguan Songshanhu Central Hospital, Dongguan, China.ORCID 0000-0003-0416-5737
Yuqiong DengDepartment of Dermatology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.ORCID 0000-0001-5678-966X
Caifeng HuangDepartment of Dermatology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.ORCID 0000-0002-7613-9899
Xiaoqing ZhaoDepartment of Dermatology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.ORCID 0000-0003-4666-8252
Sheng LiuDepartment of Dermatology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.ORCID 0000-0003-2583-8451
Xiping ChengDepartment of Dermatology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.ORCID 0000-0002-6581-8431
Dongjiang LiaoDepartment of Respiratory Medicine, State Key Laboratory of Respiratory Diseases, Guangzhou, China.ORCID 0000-0001-5950-0411
Guangzhou Medical University · CNFirst Affiliated Hospital of Guangzhou Medical University · CNState Key Laboratory of Respiratory Disease · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aims to investigate the expression patterns of mitochondrially encoded cytochrome c oxidase 1 (MT-CO1) in different organs and tissues of Materials and methods: Six-week-old female Results: The results showed that most non-immune organs/tissues (heart, lung, liver, kidneys, and intestines) showed increased MT-CO1 expression levels in younger Conclusion: Our study results suggest that lymphoid mitochondrial hyperfunction at organ level may be an important intrinsic pathogenesis in systemic lupus erythematosus activity, which may affect mitochondrial dysfunction in non-immune organs.

Indexed as

Cytochrome C oxidase subunits 1malondialdehydeoxidative stresssystemic lupus erythematosus.

Identifiers

PMID36879572
PMCPMC9985378
OpenAlexW4312780060

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.