Evidence map›Paper›PMID 36879302›Full record

ArticleExperimental hematology & oncology2023

Detection of myeloma cell-derived microvesicles: a tool to monitor multiple myeloma load.

Zhao-Yun Liu, Nan-Hao Meng, Pan-Pan Cao, Feng-Ping Peng, Jing-Yi Luo, Hao Wang, Feng-Juan Jiang, Jin Lu, Rong Fu

Open access · goldAbstract readLetter
In one paragraph

Article in Experimental hematology & oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhao-Yun Liu *Department of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin, 300052, People's Republic of China.
Nan-Hao Meng *Department of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin, 300052, People's Republic of China.
Pan-Pan CaoDepartment of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin, 300052, People's Republic of China.
Feng-Ping PengDepartment of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin, 300052, People's Republic of China.
Jing-Yi LuoDepartment of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin, 300052, People's Republic of China.
Hao WangDepartment of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin, 300052, People's Republic of China.
Feng-Juan JiangDepartment of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin, 300052, People's Republic of China.
Jin LuPeking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing, 100044, People's Republic of China.
Rong FuDepartment of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin, 300052, People's Republic of China. Furong8369@tmu.edu.cn.
Tianjin Medical University General Hospital · CNSoochow University · CN

Funding

Medjaden Academy & Research Foundation for Young Scientists MJR20221011National Natural Science Foundation of China 81900131National Natural Science Foundation of China 82000219Natural Science Foundation of Tianjin City 18JCQNJC80400Tianjin Key Medical Discipline (Specialty) Construction project TJYXZDXK-028ATianjin Municipal Education Commission 2018KJ043Tianjin Municipal Education Commission 2018KJ045Tianjin Municipal Health Commission TJWJ2021QN001Tianjin Science and Technology Program 20YFZCSY00060
6 · The paper itself

Abstract

The persistence of tumor load in multiple myeloma (MM) lead to relapse in patients achieving complete remission (CR). Appropriate and effective methods of myeloma tumor load monitoring are important for guiding clinical management. This study aimed to clarify the value of microvesicles in monitoring MM tumor load. Microvesicles in bone marrow and peripheral blood were isolated by differential ultracentrifugation and detected by flow cytometry. Western blotting was applied to assess myosin light chain phosphorylation levels. Flow cytometry to detect Ps

Identifiers

PMID36879302
PMCPMC9987071
OpenAlexW4323317161

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.