Evidence map›Paper›PMID 36879172›Full record

ArticleImmunogenetics2023

The + 3010/C single nucleotide polymorphism (rs1710) at the HLA-G 3' untranslated region is associated with a short transcript exhibiting a deletion of 92 nucleotides.

Erick C Castelli, Gabriela Sato Paes, Isabelle Mira da Silva, Philippe Moreau, Eduardo A Donadi

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Immunogenetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Erick C CastelliDepartment of Pathology, School of Medicine, São Paulo State University (Unesp), Botucatu, Brazil. erick.castelli@unesp.br.ORCID 0000-0003-2142-7196
Gabriela Sato PaesMolecular Genetics and Bioinformatics Laboratory (GeMBio) - Experimental Research Unit, School of Medicine, São Paulo State University (Unesp), Botucatu, Brazil.
Isabelle Mira da SilvaMolecular Genetics and Bioinformatics Laboratory (GeMBio) - Experimental Research Unit, School of Medicine, São Paulo State University (Unesp), Botucatu, Brazil.
Philippe MoreauCommissariat À L'Energie Atomique Et Aux Energies Alternatives, Direction de La Recherche Fondamentale, Institut de Biologie François Jacob, Service de Recherches en Hémato-ImmunologieHôpital Saint-Louis, Paris, France.
Eduardo A DonadiDivision of Clinical Immunology, Department of Medicine, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, CEP, 14049-900, Brazil.
Universidade Estadual Paulista (Unesp) · BRUniversidade de Ribeirão Preto · BRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The physiological expression of HLA-G is mainly observed in the placenta, playing an essential role in maternal-fetal tolerance. Among the HLA-G mRNA alternative transcripts, the one lacking 92 bases at the HLA-G 3' untranslated region (3'UTR), the 92bDel transcript, is more stable, is associated with increased HLA-G soluble levels, and was observed in individuals presenting a 14 bp insertion (14 bp

Indexed as

HLA-G AntigensPolymorphism, Single Nucleotide3' Untranslated RegionsFemaleGene FrequencyGenotypeHaplotypesHumansNucleotidesPregnancy3' Untranslated RegionsHLA-G AntigensNucleotides3′UTR92 base deletionAlternative splicingAlternative transcriptExpressionHLA-GPolymorphism

Identifiers

PMID36879172
OpenAlexW4323304702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.