ArticleBreast cancer research and treatment2023
Current clinical practice in the management of phyllodes tumors of the breast: an international cross-sectional study among surgeons and oncologists.
Article in Breast cancer research and treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Impact of Surgical Approach on Survival and Recurrence in Borderline and Malignant Phyllodes Tumours: A Systematic Review and Meta-Analysis.ANZ journal of surgery · 2026Pooled it
- Multidisciplinary Management of Malignant Phyllodes Tumours of the Breast: A Case-Based Illustration and Systematic Review.International journal of molecular sciences · 2026Pooled it
- UK guidelines for the management of soft tissue sarcomas.British journal of cancer · 2025Guideline
- Young Adult With Malignant Phyllodes Undergoing Adjuvant Radiotherapy With Bolus.Clinical case reports · 2026Article
- Optimal surgical margin and the efficacy of adjuvant radiotherapy in borderline and malignant phyllodes tumors: a multicenter retrospective study.Radiation oncology journal · 2026Article
- Article
- Socioeconomic Status and Survival in Sarcomas of the Breast: Nationwide Cohort Study.Annals of surgical oncology · 2026Article
- Malignant Phyllodes Tumor in Adolescent Females: A Report of Three Cases and Review of the Literature.Case reports in surgery · 2026Article
- Case Report: Recurrent malignant phyllodes tumor with malignant peripheral nerve sheath tumor-like differentiation and loss of H3K27me3/RB1 expression.Frontiers in oncology · 2026Article
- Article
- Modern management of phyllodes tumours: closing the gap between evidence and practice.Gland surgery · 2025Article
- Giant malignant phyllodes tumor: A case report.Radiology case reports · 2025Article
- Phyllodes tumors of the breast: Real world data from a multi-institution cohort.Breast (Edinburgh, Scotland) · 2025Article
- Contemporary management of phyllodes tumours of the breast: recommendations from the UK Association of Breast Surgery.The British journal of surgery · 2025Article
- Local recurrence of phyllodes tumors after surgery with wide compared to narrow margins: study protocol for a systematic review and meta-analysis.Systematic reviews · 2025Article
- Malignant Mesenchymal Tumors of the Breast: Current Challenges and New Perspectives on Primary Sarcomas and Malignant Phyllodes Tumors.Life (Basel, Switzerland) · 2025Review
- Phyllodes Tumor of the Breast: Histomorphological Transformation to High-Grade Tumor during Pregnancy and Challenging Oncoplastic Surgery.Breast care (Basel, Switzerland) · 2025Article
- Case report: rapid growth of malignant phyllodes tumor.Journal of surgical case reports · 2025Article
- Giant juvenile phyllodes tumour: a case report.Frontiers in surgery · 2025Article
- Article
Corrections and comments
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Authors and funding
27 authors at 20 institutions in 16 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePhyllodes tumors of the breast are rare fibroepithelial lesions that are classified as benign, borderline or malignant. There is little consensus on best practice for the work-up, management, and follow-up of patients with phyllodes tumors of the breast, and evidence-based guidelines are lacking.
methodsWe conducted a cross-sectional survey of surgeons and oncologists with the aim to describe current clinical practice in the management of phyllodes tumors. The survey was constructed in REDCap and distributed between July 2021 and February 2022 through international collaborators in sixteen countries across four continents.
resultsA total of 419 responses were collected and analyzed. The majority of respondents were experienced and worked in a university hospital. Most agreed to recommend a tumor-free excision margin for benign tumors, increasing margins for borderline and malignant tumors. The multidisciplinary team meeting plays a major role in the treatment plan and follow-up. The vast majority did not consider axillary surgery. There were mixed opinions on adjuvant treatment, with a trend towards more liberal regiments in patients with locally advanced tumors. Most respondents preferred a five-year follow-up period for all phyllodes tumor types.
conclusionsThis study shows considerable variation in clinical practice managing phyllodes tumors. This suggests the potential for overtreatment of many patients and the need for education and further research targeting appropriate surgical margins, follow-up time and a multidisciplinary approach. There is a need to develop guidelines that recognize the heterogeneity of phyllodes tumors.
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