Evidence map›Paper›PMID 36879007›Full record

ArticleNature biotechnology2023

Trans-segmental imaging in the spinal cord of behaving mice.

Pavel Shekhtmeyster, Daniela Duarte, Erin M Carey, Alexander Ngo, Grace Gao, Jack A Olmstead, Nicholas A Nelson, Axel Nimmerjahn

Abstract read
In one paragraph

Article in Nature biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Glial cells in neuropathic pain.Physiological reviews · 2026
    Review
  2. Spinal cord imaging in preclinical research.Neural regeneration research · 2026
    Article
  3. Article
  4. Astrocyte Regulation of Spinal Circuit Function.Journal of neurochemistry · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Advances of optical miniscopes forFrontiers in neuroscience · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pavel Shekhtmeyster *Waitt Advanced Biophotonics Center, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Daniela Duarte *Waitt Advanced Biophotonics Center, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Erin M CareyWaitt Advanced Biophotonics Center, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Alexander NgoWaitt Advanced Biophotonics Center, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Grace GaoWaitt Advanced Biophotonics Center, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Jack A OlmsteadWaitt Advanced Biophotonics Center, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Nicholas A NelsonWaitt Advanced Biophotonics Center, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Axel NimmerjahnWaitt Advanced Biophotonics Center, The Salk Institute for Biological Studies, La Jolla, CA, USA. animmerj@salk.edu.ORCID 0000-0002-0875-7855

Funding

Spinal Circuits for the Control of Dextrous MovementU19NS112959 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI GOULDING, MARTYN D · 2019 to 2023
$14.3M
Novel Genetically Encoded Indicators for Interrogating Neuron-Astrocyte Communication Across TimescalesU19NS123719 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI EROGLU, CAGLA, NIMMERJAHN, AXEL · 2021 to 2025
$10.7M
Genetically encoded indicators for large-scale sensing of neuromodulatory signaling in behaving animalsU01NS103522 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NIMMERJAHN, AXEL, TIAN, LIN · 2017 to 2019
$2.9M
Elucidating cellular activity patterns underlying spinal cord functionR01NS108034 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI NIMMERJAHN, AXEL · 2019 to 2022
$1.7M
Astrocyte Calcium Signaling in Neuropathic PainF31NS120619 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NELSON, NICHOLAS ALAN · 2020 to 2023
$122k
NINDS NIH HHS F31 NS120619NINDS NIH HHS R01 NS108034NINDS NIH HHS U01 NS103522NINDS NIH HHS U19 NS112959NINDS NIH HHS U19 NS123719
6 · The paper itself

Abstract

Spinal cord circuits play crucial roles in transmitting pain, but the underlying activity patterns within and across spinal segments in behaving mice have remained elusive. We developed a wearable widefield macroscope with a 7.9-mm

Indexed as

PainSpinal CordAnimalsDiagnostic ImagingMice

Identifiers

PMID36879007
PMCPMC11229418

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.