Evidence map›Paper›PMID 36878716›Full record

ArticleeNeuro2023

Adult Neurogenesis Is Altered by Circadian Phase Shifts and the Duper Mutation in Female Syrian Hamsters.

Michael Seifu Bahiru, Eric L Bittman

Open access · goldAbstract read
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael Seifu BahiruProgram in Neuroscience and Behavior, University of Massachusetts, Amherst, Massachusetts 01003.
Eric L BittmanProgram in Neuroscience and Behavior, University of Massachusetts, Amherst, Massachusetts 01003 elb@umass.edu.ORCID 0000-0001-6968-7590
University of Massachusetts Amherst · US

Funding

Circadian Rhythms and Internal DesynchronizationR01HL138551 · NHLBI · UNIVERSITY OF MASSACHUSETTS AMHERST · PI BITTMAN, ERIC L, HOGENESCH, JOHN B · 2018 to 2021
$2.4M
NHLBI NIH HHS R01 HL138551
6 · The paper itself

Abstract

Cell birth and survival in the adult hippocampus are regulated by a circadian clock. Rotating shift work and jet lag disrupt circadian rhythms and aggravate disease. Internal misalignment, a state in which abnormal phase relationships prevail between and within organs, is proposed to account for adverse effects of circadian disruption. This hypothesis has been difficult to test because phase shifts of the entraining cycle inevitably lead to transient desynchrony. Thus, it remains possible that phase shifts, regardless of internal desynchrony, account for adverse effects of circadian disruption and alter neurogenesis and cell fate. To address this question, we examined cell birth and differentiation in the duper Syrian hamster (

Indexed as

Circadian RhythmMotor ActivityAnimalsBromodeoxyuridineCricetinaeFemaleHumansInfant, NewbornMesocricetusMutationNeurogenesisBromodeoxyuridineadult neurogenesiscircadian rhythmsCry1cryptochromeduper mutationentrainmentjet lag

Identifiers

PMID36878716
PMCPMC10062491
OpenAlexW4323307047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.