ArticleThe American journal of clinical nutrition2023
Novel approaches to examining weight changes in pregnancies affected by obesity.
Article in The American journal of clinical nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- The role of social determinants of health in post-diagnosis gestational weight gain trajectories among women with gestational diabetes mellitus: a multicenter cohort using latent class linear mixed models.BMC public health · 2026Article
- Modeling dynamic velocity-based gestational weight gain trajectories in advanced maternal age: association with perinatal outcomes.Frontiers in medicine · 2026Article
- Gestational weight change patterns in pregnant people with obesity class I, II, and III receiving care from community-based health care centers.Annals of epidemiology · 2025Article
- Gestational weight trajectory and early offspring growth differed by gestational diabetes: a population-based cohort study.Nutrition & diabetes · 2025Article
- Reproductive risk factors across the female lifecourse and later metabolic health.Cell metabolism · 2024Review
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundCurrent gestational weight change (GWC) recommendations for obese individuals were established with limited evidence of the pattern and timing of weight change across pregnancy. Similarly, the recommendation of 5-9 kg does not differentiate by the severity of obesity.
objectivesWe sought to describe GWC trajectory classes by obesity grade and associated infant outcomes among a large, diverse cohort.
methodsThe study population included 22,355 individuals with singleton pregnancies, obesity (BMI ≥30.0 kg/m
resultsFive GWC trajectory classes were identified for each obesity grade, each with a distinct pattern of weight change before 15 wk (including loss, stability, and gain) followed by weight gain thereafter (low, moderate, and high). Two classes with high overall gain were associated with an increased risk for large for gestational age (LGA) in obesity grade 1 (IRR = 1.27; 95% CI: 1.10, 1.46; IRR = 1.47; 95% CI: 1.24, 1.74). Both high (IRR = 2.02; 95% CI: 1.61, 2.52; IRR = 1.98; 95% CI: 1.52, 2.58) and 2 moderate-gain classes (IRR = 1.40; 95% CI 1.14, 1.71; IRR = 1.51; 95% CI: 1.20, 1.90) were associated with LGA in grade 2, and only early loss/late moderate-gain class 3 (IRR = 1.30; 95% CI: 1.04, 1.62) was associated in grade 3. This class was also associated with preterm birth in grade 2. No associations were detected between GWC and small for gestational age (SGA).
conclusionsAmong the pregnancies affected by obesity, GWC was not linear or uniform. Different patterns of high gain were associated with an increased risk for LGA with the greatest magnitude in obesity grade 2, whereas GWC patterns were not associated with SGA.
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