ReviewCurrent opinion in neurobiology2023
A local circuit-basis for spatial navigation and memory processes in hippocampal area CA1.
Review in Current opinion in neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 30 citations in OpenAlex.
- Early-Life Manganese Overexposure Activates Microglial Phagocytosis through the YY1/TREM2 Axis Leading to Hippocampal Synaptic Remodeling in Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Effects of ChronicPharmaceuticals (Basel, Switzerland) · 2026Article
- Dysfunction of hippocampal cells and its role in cognitive impairment.Neural regeneration research · 2026Article
- The emergence of a novel CA1 spatial map requires direct entorhinal input.bioRxiv : the preprint server for biology · 2026Article
- TGR5 is essential for protecting from chronic stress-induced learning and memory impairments in mice by modulating inflammation associated with the gut-brain axis.Journal of neuroinflammation · 2026Article
- Trifluoperazine upregulates ACSS2-related autophagy and promotes cerebral cognitive function in rats after sleep deprivation.iScience · 2026Article
- Astrocyte Mitochondrial UCP4 Reprograms Neuronal Network Oscillations via GDNF-Dependent KCells · 2026Article
- Perceived Complexity as Normalized, Integrated, Localized Shannon Entropy.Entropy (Basel, Switzerland) · 2026Article
- Pentylenetetrazole kindling impairs place recognition memory associated with suppressing proBDNF-mediated neural information flows at the hippocampal CA3-CA1 synapses.Frontiers in pharmacology · 2026Article
- 2P-NucTag: on-demand phototagging for molecular analysis of functionally identified cortical neurons.bioRxiv : the preprint server for biology · 2025Article
- Distinct Electrophysiological Signatures Define Neuronal Subtypes in the Fasciola Cinereum.bioRxiv : the preprint server for biology · 2025Article
- Chronic postoperative pain induces contextual fear extinction dysfunction through hippocampal NMDAR/BDNF/TrkB signaling pathway in mice.Translational psychiatry · 2025Article
- The Role of Glutamatergic Neurons in Changes of Synaptic Plasticity Induced by THz Waves.Biomolecules · 2025Article
- Input/Output Relationships for the Primary Hippocampal Circuit.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Neurogenesis decreases in the offspring of mothers infected with influenza A virus.Frontiers in cellular and infection microbiology · 2025Article
- Editorial: Post-stroke cognitive decline and dementia: unraveling mechanisms, models, and biomarkers.Frontiers in stroke · 2025Article
- Dorsal raphe nucleus-hippocampus serotonergic circuit underlies the depressive and cognitive impairments in 5×FAD male mice.Translational neurodegeneration · 2024Article
- Remapping revisited: how the hippocampus represents different spaces.Nature reviews. Neuroscience · 2024Review
- Chronic stress induces Alzheimer's disease-like pathologies through DNA damage-Chk1-CIP2A signaling.Aging · 2024Article
- Reward Expectation Reduces Representational Drift in the Hippocampus.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The hippocampus is a multi-stage neural circuit that is critical for memory formation. Its distinct anatomy has long inspired theories that rely on local interactions between neurons within each subregion in order to perform serial operations important for memory encoding and storage. These local computations have received less attention in CA1 area, the primary output node of the hippocampus, where excitatory neurons are thought to be only very sparsely interconnected. However, recent findings have demonstrated the power of local circuitry in CA1, with evidence for strong functional interactions among excitatory neurons, regulation by diverse inhibitory microcircuits, and novel plasticity rules that can profoundly reshape the hippocampal ensemble code. Here we review how these properties expand the dynamical repertoire of CA1 beyond the confines of feedforward processing, and what implications they have for hippocampo-cortical functions in memory formation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.