Evidence map›Paper›PMID 36878110›Full record

Trial reportEuropean journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society2023

Safety and feasibility of transcranial direct current stimulation stratified by corticospinal organization in children with hemiparesis.

Samuel T Nemanich, Daniel H Lench, Ellen N Sutter, Jesse L Kowalski, Sunday M Francis, Gregg D Meekins, Linda E Krach, Tim Feyma, Bernadette T Gillick

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Samuel T NemanichDepartment of Occupational Therapy, Marquette University, 1700 West Wells St., Room 140, Milwaukee, WI, 53201, USA. Electronic address: sam.nemanich@marquette.edu.
Daniel H LenchDepartment of Neurology, Medical University of South Carolina, 208B Rutledge Avenue, Charleston, SC, 29425, USA.
Ellen N SutterDepartment of Rehabilitation Medicine, University of Minnesota, 420 Delaware St SE, MMC 388, Minneapolis, MN, 55455, USA.
Jesse L KowalskiDepartment of Physical Medicine and Rehabilitation, Harvard Medical School, 79/96 13th Street, Charlestown, MA, United States.
Sunday M FrancisDepartment of Psychiatry and Behavioral Sciences, University of Minnesota, 2312 S. 6th St.Floor 2, Suite F-275, Minneapolis, MN, 55454, USA.
Gregg D MeekinsDepartment of Neurology, University of Minnesota, 420 Delaware St SE, MMC 295, Minneapolis, MN, 55455, USA.
Linda E KrachDepartment of Rehabilitation Medicine, University of Minnesota, 420 Delaware St SE, MMC 388, Minneapolis, MN, 55455, USA; Rehabilitation Medicine, Gillette Children's Specialty Healthcare, 200 University Ave E, St Paul, MN, 55101, USA.
Tim FeymaNeurology, Gillette Children's Specialty Healthcare, 200 University Ave E, St Paul, MN, 55101, USA.
Bernadette T GillickDepartment of Rehabilitation Medicine, University of Minnesota, 420 Delaware St SE, MMC 388, Minneapolis, MN, 55455, USA; Department of Pediatrics, University of Wisconsin-Madison, 1500 Highland Avenue, Madison, WI, 53705, USA.
University of Minnesota · USGillette Children's Specialty Healthcare · USHarvard University · USMarquette University · USMedical University of South Carolina · US

Funding

Non-invasive Neuromodulation Unit (NNU)ZIAMH002955 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI ZARATE, CARLOS · 2016 to 2025
$40.3M
Techniques DevelopmentP2CHD086844 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI THOMPSON, AIKO · 2015 to 2024
$12.7M
TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Mehmet Akcakaya · 2019 to 2026
$11.7M
Institutional Center Cores for Advanced NeuroimagingP30NS076408 · NINDS · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2020
$4.2M
Using Computation to Achieve Breakthroughs in NeuroscienceT32MH115886 · NIMH · UNIVERSITY OF MINNESOTA · PI REDISH, A DAVID · 2018 to 2022
$1.7M
Novel Neuromodulatory Intervention in the Rehabilitation of Pediatric HemiparesisK01HD078484 · NICHD · UNIVERSITY OF MINNESOTA · PI GILLICK, BERNADETTE THERESE · 2014 to 2018
$654k
High Performance Connectome Upgrade for Human 3T MR ScannerS10OD017974 · OD · UNIVERSITY OF MINNESOTA · PI LIM, KELVIN O. · 2014 to 2014
$600k
NIBIB NIH HHS P41 EB027061NICHD NIH HHS K01 HD078484NICHD NIH HHS P2C HD086844NIH HHS S10 OD017974NIMH NIH HHS T32 MH115886NINDS NIH HHS P30 NS076408
6 · The paper itself

Abstract

Children with hemiparesis (CWH) due to stroke early in life face lifelong impairments in motor function. Transcranial direct current stimulation (tDCS) may be a safe and feasible adjuvant therapy to augment rehabilitation. Given the variability in outcomes following tDCS, tailored protocols of tDCS are required. We evaluated the safety, feasibility, and preliminary effects of a single session of targeted anodal tDCS based on individual corticospinal tract organization on corticospinal excitability. Fourteen CWH (age = 13.8 ± 3.63) were stratified into two corticospinal organization subgroups based on transcranial magnetic stimulation (TMS)-confirmed motor evoked potentials (MEP): ipsilesional MEP presence (MEP

Indexed as

Motor CortexStrokeTranscranial Direct Current StimulationAdolescentChildEvoked Potentials, MotorFeasibility StudiesHumansTranscranial Magnetic StimulationBrain excitabilityHemiparesisMotor evoked potentialPerinatal strokeTranscranial direct current stimulation

Identifiers

PMID36878110
PMCPMC10117060
OpenAlexW4322627136

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.