Evidence map›Paper›PMID 36878055›Full record

ArticleThe American journal of cardiology2023

Physician Perspectives on the Use of Beta Blockers in Heart Failure With Preserved Ejection Fraction.

Mahad Musse, Jennifer D Lau, Brian Yum, Laura C Pinheiro, Hannah Curtis, Timothy Anderson, Michael A Steinman, Markus Meyer, Michael Dorsch, Scott L Hummel and 1 more

Open access · greenAbstract read
In one paragraph

Article in The American journal of cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Mahad MusseDepartment of Medicine, Weill Cornell Medicine, New York, New York.
Jennifer D LauDepartment of Medicine, Weill Cornell Medicine, New York, New York.
Brian YumTexas Heart Institute, Houston, Texas.
Laura C PinheiroDepartment of Medicine, Weill Cornell Medicine, New York, New York.
Hannah CurtisDepartment of Medicine, Weill Cornell Medicine, New York, New York.
Timothy AndersonDivision of General Medicine, Beth Israel Deaconess, Boston, Massachusetts.
Michael A SteinmanDivision of Geriatrics, University of California San Francisco; San Francisco Veterans Affairs Medical Center, San Francisco, California.
Markus MeyerUniversity of Minnesota, Minneapolis, Minnesota.
Michael DorschCollege of Pharmacy, University of Michigan, Ann Arbor, Michigan.
Scott L HummelUniversity of Michigan Frankel Cardiovascular Center; VA Ann Arbor Health System, Ann Arbor, Michigan.
Parag GoyalDepartment of Medicine, Weill Cornell Medicine, New York, New York. Electronic address: pag9051@med.cornell.edu.
Cornell University · USUniversity of Michigan · USSan Francisco VA Medical Center · USUniversity of Minnesota System · US

Funding

VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Louise C. Walter · 2013 to 2026
$19.9M
U.S. Deprescribing Research NetworkR24AG064025 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI BOYD, CYNTHIA MELINDA, STEINMAN, MICHAEL A. · 2019 to 2023
$9.9M
Prescribing cascades in older adults with and without dementiaK24AG049057 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEINMAN, MICHAEL A. · 2015 to 2025
$1.8M
A Novel Deprescribing Intervention for Heart Failure with Preserved Ejection Fraction (HFpEF): A Prototype for Older Adults with Multimorbidity and PolypharmacyK76AG064428 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI GOYAL, PARAG · 2020 to 2024
$1.1M
NIA NIH HHS K24 AG049057NIA NIH HHS K76 AG064428NIA NIH HHS P30 AG044281NIA NIH HHS R24 AG064025
6 · The paper itself

Abstract

β-blockers are commonly used in heart failure with preserved ejection fraction (HFpEF), even in the absence of a compelling indication and despite the potential to cause harm. Identifying reasons for β-blocker prescription in HFpEF could permit the development of strategies to reduce unnecessary use and potentially improve medication prescribing patterns in this vulnerable population. We administered an online survey regarding β-blocker prescribing behavior to physicians trained in internal medicine or geriatrics (noncardiology physicians) and to cardiologists at 2 large academic medical centers. The survey assessed the reasons for β-blocker initiation, agreement regarding initiation and/or continuation of β-blockers by another clinician, and deprescribing behavior. The response rate was 28.2% (n = 231). Among respondents, 68.2% reported initiating β-blockers in patients with HFpEF. The most common reason for initiating a β-blocker was for treatment of an atrial arrhythmia. Notably, 23.7% of physicians reported initiating a β-blocker without an evidence-based indication. When a β-blocker was considered not necessary, 40.1% of physicians reported they were rarely or never willing to deprescribe. The most common reason for not deprescribing a β-blocker when the physician felt that a β-blocker was unnecessary was the concern about interfering with another physicians' treatment plan (76.6%). In conclusion, a significant proportion of noncardiology physicians and cardiologists report prescribing β-blockers to patients with HFpEF, even when evidence-based indications are absent, and rarely deprescribe β-blockers in these scenarios.

Indexed as

CardiologistsHeart FailureAdrenergic beta-AntagonistsDrug PrescriptionsHumansStroke VolumeAdrenergic beta-Antagonists

Identifiers

PMID36878055
PMCPMC10114214
OpenAlexW4323111910

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.