ArticleProceedings of the National Academy of Sciences of the United States of America2023
Oligomerization of a plant helper NLR requires cell-surface and intracellular immune receptor activation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- The BTB/POZ-MATH Protein ZmBPM1 Interacts With Autophagy-related Protein ZmATG6 and Modulates the NLR Protein Rp1-D21-Mediated Defense Response in Maize.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- Plant NLRs are getting into higher-order architectures.The Plant journal : for cell and molecular biology · 2026Review
- Unraveling plant immunity: from pathogen perception to resistance engineering.Science China. Life sciences · 2026Review
- Molecular mechanisms of plant NLR activation and signalling.The Plant journal : for cell and molecular biology · 2026Review
- Motif-based substrate mapping of the receptor-like cytoplasmic kinase BIK1 reveals novel components and regulatory nodes of plant immunity.Nature plants · 2026Article
- Blue Native-PAGE Assay of NLR Protein Complexes Combined with Genetic Complementation in Nicotiana benthamiana.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Manipulation of the nucleotide pool in human, bacterial and plant immunity.Nature reviews. Immunology · 2026Review
- Orchestration of plant PRR- and NLR-mediated immunity: Protein kinases and beyond.Molecular cell · 2025Review
- Under control: A WRKY transcription factor positively regulates the expression of a helper NLR immune receptor in Nicotiana benthamiana.Plant physiology · 2025Article
- Living with temperature changes: Salicylic acid at the crossroads of plant immunity and temperature resilience.Science advances · 2025Review
- Coordinated actions of NLR-assembled and glutamate receptor-like calcium channels in plant effector-triggered immunity.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Activation and suppression mechanisms of the NRG1 helper NLRs.Journal of integrative plant biology · 2025Article
- Domestication Reduces Plant Immune Receptor Gene Repertoires Across Lineages.Genome biology and evolution · 2025Article
- Article
- A cell wall-associated kinase phosphorylates NLR immune receptor to negatively regulate resistosome formation.Nature plants · 2025Article
- Molecular tipping points in plant cell surface HQuantitative plant biology · 2025Review
- Unveiling resistance expression profile to powdery mildew in wheat via Bulked Segregant RNA-Seq.BMC plant biology · 2024Article
- A disease resistance protein triggers oligomerization of its NLR helper into a hexameric resistosome to mediate innate immunity.Science advances · 2024Article
- Activation of an atypical plant NLR with an N-terminal deletion initiates cell death at the vacuole.EMBO reports · 2024Article
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Authors and funding
8 authors.
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Abstract
Plant disease resistance involves both detection of microbial molecular patterns by cell-surface pattern recognition receptors and detection of pathogen effectors by intracellular NLR immune receptors. NLRs are classified as sensor NLRs, involved in effector detection, or helper NLRs required for sensor NLR signaling. TIR-domain-containing sensor NLRs (TNLs) require helper NLRs NRG1 and ADR1 for resistance, and helper NLR activation of defense requires the lipase-domain proteins EDS1, SAG101, and PAD4. Previously, we found that NRG1 associates with EDS1 and SAG101 in a TNL activation-dependent manner [X. Sun
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